ChemSpider 2D Image | HYDRALAZINE HYDROCHLORIDE | C8H9ClN4

HYDRALAZINE HYDROCHLORIDE

  • Molecular FormulaC8H9ClN4
  • Average mass196.637 Da
  • Monoisotopic mass196.051575 Da
  • ChemSpider ID8985

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-hydrazinophtalazine chlorhydrate
1-Hydrazinophtalazine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
1-Hydrazinophthalazine hydrochloride (1:1) [ACD/IUPAC Name]
1-Hydrazinophthalazinhydrochlorid [German]
1-Hydrazinophthalazinhydrochlorid (1:1) [German] [ACD/IUPAC Name]
1-hydrazinylphthalazine hydrochloride (1:1)
206-151-0 [EINECS]
304-20-1 [RN]
Apresoline [Trade name]
FD171B778Y
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BPI-103 [DBID]
CCRIS 334 [DBID]
D01302 [DBID]
EU-0100593 [DBID]
H1753_SIGMA [DBID]
MFCD01457387 [DBID]
NSC 89394 [DBID]
Prestwick_610 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      22-40-63 Alfa Aesar B22995
      36/37 Alfa Aesar B22995
      6.1 Alfa Aesar B22995
      Danger Alfa Aesar B22995
      DANGER: POISON, irritates skin, eyes, lungs Alfa Aesar B22995
      H301-H351-H361 Alfa Aesar B22995
      P281-P301+P310-P308+P313-P321-P405-P501a Alfa Aesar B22995

    • Target Organs:

      Others TargetMol T1613

    • Chemical Class:

      The hydrochloride salt of hydralazine; a direct-acting vasodilator that is used as an antihypertensive agent. ChEBI CHEBI:31672

    • Bio Activity:

      AO;P4H TargetMol T1613
      Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent. MedChem Express
      Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.; Target: Others; Hydralazine (apresoline) is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles. MedChem Express HY-B0464
      Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.;Target: Hydralazine (apresoline) is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles. By relaxing vascular smooth muscle, vasodilators act to decrease peripheral resistance, thereby lowering blood pressure and decreasing afterload. However, this only has a short term effect on blood pressure, as the system will reset to the previous, high blood pressure necessary to maintain pressure in the kidney necessary for natriuresis. The long term effect of antihypertensive drugs comes from their effects on the pressure natriuresis curve. It belongs to the hydrazinophthalazine class of drugs [1]. Hydralazine may reduce blood pressure when compared to placebo in patients with primary hypertension, however this data is based on before and after studies, not RCTs. Furthermore, its effect on clinical outcomes re MedChem Express HY-B0464
      Others MedChem Express HY-B0464
      Others TargetMol T1613

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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