ChemSpider 2D Image | Aminophylline | C16H24N10O4

Aminophylline

  • Molecular FormulaC16H24N10O4
  • Average mass420.426 Da
  • Monoisotopic mass420.198212 Da
  • ChemSpider ID9062

More details:

Featured data source
The Merck Index Online

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(Theophylline)2 ?? Ethylenediamine
1,2-Ethanediamine compd. with 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:2)
1,3-Dimethyl-3,7-dihydro-1H-purin-2,6-dion --1,2-ethandiamin (2:1) [German] [ACD/IUPAC Name]
1,3-Dimethyl-3,7-dihydro-1H-purin-2,6-dion-ethan-1,2-diamin(2:1)
1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione - 1,2-ethanediamine (2:1) [ACD/IUPAC Name]
1,3-Diméthyl-3,7-dihydro-1H-purine-2,6-dione - 1,2-éthanediamine (2:1) [French] [ACD/IUPAC Name]
1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione - ethane-1,2-diamine (2:1)
1,3-diméthyl-3,7-dihydro-1H-purine-2,6-dione - éthane-1,2-diamine (2:1)
1,3-Dimethyl-3,9-dihydro-1H-purine-2,6-dione - ethane-1,2-diamine (2:1)
1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1) [ACD/Index Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

A1755_SIGMA [DBID]
BY 108 [DBID]
D00227 [DBID]
EU-0100014 [DBID]
HSDB 221 [DBID]
Lopac-A-1755 [DBID]
NCGC00016113-01 [DBID]
NCGC00016113-02 [DBID]
NSC 7919 [DBID]
Prestwick_93 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      22 LKT Labs [A5134]
      Danger Biosynth W-106881
      GHS06 Biosynth W-106881
      H301 Biosynth W-106881
      H301 LKT Labs [A5134]
      P301+P310 Biosynth W-106881
      R03DA05 Wikidata Q471763
      UN 2811 6.1/PG 3 LKT Labs [A5134]
      Xn Abblis Chemicals AB1009250
      Xn LKT Labs [A5134]

    • Target Organs:

      PDE inhibitor; Adenosine receptor antagonist;HDAC2 activator TargetMol T1681

    • Drug Status:

      approved BIONET-Key Organics KS-5340

    • Bio Activity:

      Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD. MedChem Express
      Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD.; Target: Phosphodiesterase; Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. MedChem Express HY-B0140
      Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD.;Target: PhosphodiesteraseAminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD. It is used off-label as a reversal agent during nuclear stress testing. Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor.Adenosine is an endogenous extracellular messenger that can regulate myocardial oxygen needs. It acts through cellular surface receptors which effect intracellular signalling pathways to increase coronary artery blood flow, slow heart rate, block atrioventricular node conduction, suppress cardiac automaticity, and decrease MedChem Express HY-B0140
      Metabolic Enzyme/Protease; MedChem Express HY-B0140
      Metabolism; GPCR/G Protein; Chromatin/Epigenetic TargetMol T1681
      Others MedChem Express HY-B0140
      PDE MedChem Express HY-B0140
      PDE; Adenosine receptor;HDAC2 TargetMol T1681

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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