Found 1 result

Search term: RBJCBXAXUHCWBR (Found by InChIKey (skeleton match))
ChemSpider 2D Image | Methyl 2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate hydrochloride (1:1) | C31H30ClN5O7

Methyl 2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate hydrochloride (1:1)

  • Molecular FormulaC31H30ClN5O7
  • Average mass620.052 Da
  • Monoisotopic mass619.183350 Da
  • ChemSpider ID8027754

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2,7-Naphthyridine-3-carboxylic acid, 1,2-dihydro-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-, methyl ester, hydrochloride (1:1) [ACD/Index Name]
2-[(2-Méthyl-4-pyridinyl)méthyl]-1-oxo-8-(2-pyrimidinylméthoxy)-4-(3,4,5-triméthoxyphényl)-1,2-dihydro-2,7-naphtyridine-3-carboxylate de méthyle, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
Methyl 2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate hydrochloride (1:1) [ACD/IUPAC Name]
Methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate hydrochloride (1:1)
Methyl-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridin-3-carboxylathydrochlorid (1:1) [German] [ACD/IUPAC Name]
[324572-93-2] [RN]
1,2-Dihydro-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylic acid methyl ester hydrochloride
2-(2-Methylpyridin-4-yl)methyl-4-(3,4,5-trimethoxyphenyl)-8-(pyrimidin-2-yl)methoxy-1,2-dihydro-1-oxo-2,7-naphthyridine-3-carboxylic acid methyl ester hydrochloride
324572-92-1 [RN]
324572-93-2 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

T-0156 [DBID]
EU-0101212 [DBID]
T8067_SIGMA [DBID]
  • Experimental Physico-chemical Properties

    • Experimental Solubility:

      Soluble to 25 mM in ethanol and to 25 mM in DMSO Tocris Bioscience 1676
      Soluble to 25 mM in ethanol with gentle warming and to 25 mM in DMSO with gentle warming Tocris Bioscience 1676
  • Miscellaneous

    • Safety:

      Sold with the permission of Tanabe Seiyaku Co. Ltd. Tocris Bioscience 1676

    • Bio Activity:

      Enzymes Tocris Bioscience 1676
      Highly potent, selective PDE5 inhibitor Tocris Bioscience 1676
      Phosphodiesterases Tocris Bioscience 1676
      Potent and selective inhibitor of phosphodiesterase type 5 (PDE5); more selective than sildenafil (IC50 values are 0.23, 56 and > 63000 nM for T 0156 and 3.6, 29 and > 270 nM for sildenafil at PDE5, P DE6 and PDEs 1 - 4 respectively). Selective over 30 other enzymes and receptors (IC50 > 10 mM) and potentiates electrical field stimulation-induced relaxation of isolated rabbit corpus cavernosum. Act ive in vivo. Tocris Bioscience 1676
      Potent and selective inhibitor of phosphodiesterase type 5 (PDE5); more selective than sildenafil (IC50 values are 0.23, 56 and > 63000 nM for T 0156 and 3.6, 29 and > 270 nM for sildenafil at PDE5, PDE6 and PDEs 1 - 4 respectively). Selective over 30 other enzymes and receptors (IC50 > 10 mM) and potentiates electrical field stimulation-induced relaxation of isolated rabbit corpus cavernosum. Active in vivo. Tocris Bioscience 1676

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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