Found 1 result

Search term: MF = 'C_{43}H_{42}ClFN_{4}O_{10}S_{3}'
ChemSpider 2D Image | Lapatinib Ditosylate | C43H42ClFN4O10S3

Lapatinib Ditosylate

  • Molecular FormulaC43H42ClFN4O10S3
  • Average mass925.461 Da
  • Monoisotopic mass924.173584 Da
  • ChemSpider ID8116714

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

388082-77-7 [RN]
4-Methylbenzolsulfonsäure --N-{3-chlor-4-[(3-fluorbenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-chinazolinamin (2:1) [German] [ACD/IUPAC Name]
4-Methylbenzolsulfonsäure--N-{3-chlor-4-[(3-fluorbenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]chinazolin-4-amin(2:1)
4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-, 4-methylbenzenesulfonate (1:2) [ACD/Index Name]
4WK72K94MC
Acide 4-méthylbenzènesulfonique - N-{3-chloro-4-[(3-fluorobenzyl)oxy]phényl}-6-[5-({[2-(méthylsulfonyl)éthyl]amino}méthyl)-2-furyl]-4-quinazolinamine (2:1) [French] [ACD/IUPAC Name]
acide 4-méthylbenzènesulfonique - N-{3-chloro-4-[(3-fluorobenzyl)oxy]phényl}-6-[5-({[2-(méthylsulfonyl)éthyl]amino}méthyl)furan-2-yl]quinazolin-4-amine (2:1)
bis(4-methylbenzene-1-sulfonic acid)
bis(4-methylbenzene-1-sulfonic acid); N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine
Lapatinib Ditosylate [USAN]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

GW 572016 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      EGFR MedChem Express HY-50898A
      JAK/STAT Signaling MedChem Express HY-50898A
      JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; MedChem Express HY-50898A
      Lapatinib ditosylate(GW-572016 ditosylate) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. MedChem Express
      Lapatinib ditosylate(GW-572016 ditosylate) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.; IC50 Value: 10.8 nM (EGFR); 9.2 nM (ErbB2); Target: EGFR/ErbB2; Lapatinib ditosylate is a selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases. MedChem Express HY-50898A
      Lapatinib ditosylate(GW-572016 ditosylate) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.;IC50 Value: 10.8 nM (EGFR); 9.2 nM (ErbB2);Target: EGFR/ErbB2Lapatinib ditosylate is a selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases. ErbB-2 and EGFR dual tyrosine kinases are growth promoting factors that are over expressed in some breast cancer cell lines. Research studies have reported that Lapatinib Ditosylate can inhibit breast cancer cell proliferation. MedChem Express HY-50898A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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