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Search term: C4H10O
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Inherent Properties, Identifiers and References
ChemSpider ID: 10709
Empirical Formula: C4H10O
Molecular Weight: 74.1216
Nominal Mass: 74 Da
Average Mass: 74.1216 Da
Monoisotopic Mass: 74.073165 Da
Quick Links: Permalink Similar Isomers
Systematic Name: 1-methoxypropane
SMILES: O(CCC)C
InChI: InChI=1/C4H10O/c1-3-4-5-2/h3-4H2,1-2H3
InChIKey: VNKYTQGIUYNRMY-UHFFFAOYAK
(Details...) Wikipedia Article(s)
Methoxypropane, or methyl propyl ether, is an ether once used as a general anaesthetic. It is a clear colorless flammable liquid with a boiling point of 38.8 °C. Marketed under the trade names Metopryl and Neothyl, methoxypropane was used as an alternative to diethyl ether because of its greater potency. Its use as an anaesthetic has since been supplanted by modern halogenated ethers which are much less flammable. Read more... or Edit at Wikipedia...
Methoxypropane, or methyl propyl ether, is an ether once used as a general anaesthetic. It is a clear colorless flammable liquid with a boiling point of 38.8 °C. Marketed under the trade names Metopryl and Neothyl, methoxypropane was used as an alternative to diethyl ether because of its greater potency. Its use as an anaesthetic has since been supplanted by modern halogenated ethers which are much less flammable. Read more... or Edit at Wikipedia...
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Names and Synonyms

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209-158-7 [EINECS/ELINCS]

557-17-5 [RN]

Neo-thyl

1-Methoxy​propane

alpha-Met​hoxy prop​ane

Ether, me​thyl prop​yl

Methyl n-​propyl et​her

Methyl pr​opyl ether

Methyl pr​opyl ethe​r [UN2612​] [Flamm​able liqu​id]

Metopryl [Wiki]

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Database ID(s)

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(Details...) Predicted Properties
LogP: ACD/LogP: 0.98
XLogP: 0.80
ALOGPS: 0.90
# of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 0.98 ACD/LogD (pH 7.4): 0.98
ACD/BCF (pH 5.5): 3.28 ACD/BCF (pH 7.4): 3.28
ACD/KOC (pH 5.5): 81.43 ACD/KOC (pH 7.4): 81.43
#H bond acceptors: 1 #H bond donors: 0
#Freely Rotating Bonds: 2 Polar Surface Area: 9.23 Å2
Index of Refraction: 1.36 Molar Refractivity: 22.32 cm3
Molar Volume: 100.9 cm3 Polarizability: 8.85 10-24cm3
Surface Tension: 19 dyne/cm Density: 0.734 g/cm3
Flash Point: °C Enthalpy of Vaporization: 26.75 kJ/mol
Boiling Point: 40.1 °C at 760 mmHg Vapour Pressure: 440 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  1.05
    Log Kow (Exper. database match) =  1.21
       Exper. Ref:  Hansch,C et al. (1995)

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  47.02  (Adapted Stein & Brown method)
    Melting Pt (deg C):  -101.15  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  458  (Mean VP of Antoine & Grain methods)
    BP  (exp database):  39.1 deg C
    VP  (exp database):  4.65E+02 mm Hg at 25 deg C

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  1.239e+004
       log Kow used: 1.21 (expkow database)
       no-melting pt equation used
     Water Sol (Exper. database match) =  3.05e+004 mg/L (25 deg C)
        Exper. Ref:  YALKOWSKY,SH & DANNENFELSER,RM (1992)

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  47555 mg/L
    Wat Sol (Exper. database match) =  30500.00
       Exper. Ref:  YALKOWSKY,SH & DANNENFELSER,RM (1992)

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   1.52E-003  atm-m3/mole
   Group Method:   9.52E-004  atm-m3/mole
   Exper Database: 1.49E-03  atm-m3/mole
 Henrys LC [VP/WSol estimate using EPI values]:  3.605E-003 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  1.21  (exp database)
  Log Kaw used:  -1.215  (exp database)
      Log Koa (KOAWIN v1.10 estimate):  2.425
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.3649
   Biowin2 (Non-Linear Model)     :   0.1864
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   3.0267  (weeks       )
   Biowin4 (Primary Survey Model) :   3.7311  (days-weeks  )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.5927
   Biowin6 (MITI Non-Linear Model):   0.7643
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.4717
 Ready Biodegradability Prediction:   YES

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  6.2E+004 Pa (465 mm Hg)
  Log Koa (Koawin est  ): 2.425
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  4.84E-011 
       Octanol/air (Koa) model:  6.53E-011 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1.75E-009 
       Mackay model           :  3.87E-009 
       Octanol/air (Koa) model:  5.23E-009 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =  11.2737 E-12 cm3/molecule-sec
      Half-Life =     0.949 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =    11.385 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Fraction sorbed to airborne particulates (phi): 2.81E-009 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  4.395
      Log Koc:  0.643 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 0.232 (BCF = 1.705)
       log Kow used: 1.21 (expkow database)

 Volatilization from Water:
    Henry LC:  0.00149 atm-m3/mole  (Henry experimental database)
    Half-Life from Model River:      1.217  hours
    Half-Life from Model Lake :      85.46  hours   (3.561 days)

 Removal In Wastewater Treatment:
    Total removal:              38.91  percent
    Total biodegradation:        0.06  percent
    Total sludge adsorption:     1.24  percent
    Total to Air:               37.60  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       17.4            22.8         1000       
   Water     61.7            360          1000       
   Soil      20.8            720          1000       
   Sediment  0.13            3.24e+003    0          
     Persistence Time: 111 hr