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Search term: OFZGTWQIVANFBY-NTMALXAHBO
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Inherent Properties, Identifiers and References
ChemSpider ID: 4654373
Empirical Formula: C24H33Cl2N5O
Molecular Weight: 478.4577
Nominal Mass: 477 Da
Average Mass: 478.4577 Da
Monoisotopic Mass: 477.206216 Da
Systematic Name: 4-[1-[1-[(Z)-1-tert-butyl-3-(2,4-dichlorophenyl)prop-2-enyl]tetra​zol-5-yl]cyclohexyl]morpholine
SMILES: Clc1ccc(c(Cl)c1)\C=C/C(n2nnnc2C4(N3CCOCC3)CCCCC4)C(C)(C)C
InChI: InChI=1/C24H33Cl2N5O/c1-23(2,3)21(10-8-18-7-9-19(25)17-20(18)26)3​1-22(27-28-29-31)24(11-5-4-6-12-24)30-13-15-32-16-14-30/h7-10,17,​21H,4-6,11-16H2,1-3H3/b10-8-
InChIKey: OFZGTWQIVANFBY-NTMALXAHBO
Std. InChI: InChI=1S/C24H33Cl2N5O/c1-23(2,3)21(10-8-18-7-9-19(25)17-20(18)26)​31-22(27-28-29-31)24(11-5-4-6-12-24)30-13-15-32-16-14-30/h7-10,17​,21H,4-6,11-16H2,1-3H3/b10-8-
Std. InChIKey: OFZGTWQIVANFBY-NTMALXAHSA-N
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

4-(1-{1-[​1-tert-bu​tyl-3-(2,​4-dichlor​ophenyl)-​2-propen-​1-yl]-1H-​tetrazol-​5-yl}cycl​ohexyl)mo​rpholine

ACD/LogP: 5.52 # of Rule of 5 Violations: 1
ACD/LogD (pH 5.5): 5.34 ACD/LogD (pH 7.4): 5.51
ACD/BCF (pH 5.5): 6177.37 ACD/BCF (pH 7.4): 9087.41
ACD/KOC (pH 5.5): 16093.88 ACD/KOC (pH 7.4): 23675.42
#H bond acceptors: 6 #H bond donors: 0
#Freely Rotating Bonds: 6 Polar Surface Area: 56.07 Å2
Index of Refraction: 1.619 Molar Refractivity: 131.13 cm3
Molar Volume: 373.5 cm3 Polarizability: 51.98 10-24cm3
Surface Tension: 46.1 dyne/cm Density: 1.28 g/cm3
Flash Point: 336.8 °C Enthalpy of Vaporization: 93.62 kJ/mol
Boiling Point: 633.3 °C at 760 mmHg Vapour Pressure: 6.06E-16 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  5.30

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  533.17  (Adapted Stein & Brown method)
    Melting Pt (deg C):  228.09  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  2.6E-011  (Modified Grain method)
    Subcooled liquid VP: 3.94E-009 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  0.2971
       log Kow used: 5.30 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  5.9869 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Aliphatic Amines

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   8.91E-012  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  5.509E-011 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  5.30  (KowWin est)
  Log Kaw used:  -9.439  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  14.739
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :  -0.7656
   Biowin2 (Non-Linear Model)     :   0.0000
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   1.0409  (recalcitrant)
   Biowin4 (Primary Survey Model) :   2.2221  (months      )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.4820
   Biowin6 (MITI Non-Linear Model):   0.0001
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model): -3.8871
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  5.25E-007 Pa (3.94E-009 mm Hg)
  Log Koa (Koawin est  ): 14.739
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  5.71 
       Octanol/air (Koa) model:  135 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.995 
       Mackay model           :  0.998 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 208.2998 E-12 cm3/molecule-sec [Cis-isomer]
      OVERALL OH Rate Constant = 215.8998 E-12 cm3/molecule-sec [Trans-isomer]
      Half-Life =    0.616 Hrs (12-hr day; 1.5E6 OH/cm3) [Cis-isomer]
      Half-Life =    0.594 Hrs (12-hr day; 1.5E6 OH/cm3) [Trans-isomer]
   Ozone Reaction:
      OVERALL Ozone Rate Constant =     6.825000 E-17 cm3/molecule-sec [Cis-]
      OVERALL Ozone Rate Constant =    13.650000 E-17 cm3/molecule-sec [Trans-]
      Half-Life =     4.030 Hrs (at 7E11 mol/cm3) [Cis-isomer]
      Half-Life =     2.015 Hrs (at 7E11 mol/cm3) [Trans-isomer]
   Fraction sorbed to airborne particulates (phi): 0.996 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  2.688E+006
      Log Koc:  6.429 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 3.382 (BCF = 2412)
       log Kow used: 5.30 (estimated)

 Volatilization from Water:
    Henry LC:  8.91E-012 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 1.437E+008  hours   (5.989E+006 days)
    Half-Life from Model Lake : 1.568E+009  hours   (6.533E+007 days)

 Removal In Wastewater Treatment:
    Total removal:              85.18  percent
    Total biodegradation:        0.73  percent
    Total sludge adsorption:    84.45  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.00248         0.944        1000       
   Water     2.74            4.32e+003    1000       
   Soil      71.9            8.64e+003    1000       
   Sediment  25.4            3.89e+004    0          
     Persistence Time: 8.51e+003 hr