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Search term: XHHMRKDKEQLSMP-UHFFFAOYAI
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Inherent Properties, Identifiers and References
ChemSpider ID: 2854126
Empirical Formula: C14H12FN
Molecular Weight: 213.2502
Nominal Mass: 213 Da
Average Mass: 213.2502 Da
Monoisotopic Mass: 213.095378 Da
Systematic Name: 5-fluoro-2-phenyl-indoline
SMILES: Fc1cc3c(cc1)NC(c2ccccc2)C3
InChI: InChI=1/C14H12FN/c15-12-6-7-13-11(8-12)9-14(16-13)10-4-2-1-3-5-10​/h1-8,14,16H,9H2
InChIKey: XHHMRKDKEQLSMP-UHFFFAOYAI
Std. InChI: InChI=1S/C14H12FN/c15-12-6-7-13-11(8-12)9-14(16-13)10-4-2-1-3-5-1​0/h1-8,14,16H,9H2
Std. InChIKey: XHHMRKDKEQLSMP-UHFFFAOYSA-N
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ACD/LogP: 3.30 # of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 3.26 ACD/LogD (pH 7.4): 3.3
ACD/BCF (pH 5.5): 174.83 ACD/BCF (pH 7.4): 188.83
ACD/KOC (pH 5.5): 1371.62 ACD/KOC (pH 7.4): 1481.45
#H bond acceptors: 1 #H bond donors: 1
#Freely Rotating Bonds: 1 Polar Surface Area: 2
Index of Refraction: 1.588 Molar Refractivity: 61.6 cm3
Molar Volume: 182.9 cm3 Polarizability: 24.42 10-24cm3
Surface Tension: 42.3 dyne/cm Density: 1.165 g/cm3
Flash Point: 152.2 °C Enthalpy of Vaporization: 57.03 kJ/mol
Boiling Point: 328 °C at 760 mmHg Vapour Pressure: 0.000195 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  3.36

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  321.17  (Adapted Stein & Brown method)
    Melting Pt (deg C):  99.36  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  0.000119  (Modified Grain method)
    Subcooled liquid VP: 0.00063 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  510.7
       log Kow used: 3.36 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  246.42 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Aliphatic Amines

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   2.48E-006  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  6.538E-008 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  3.36  (KowWin est)
  Log Kaw used:  -3.994  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  7.354
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.9279
   Biowin2 (Non-Linear Model)     :   0.9473
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.7744  (weeks       )
   Biowin4 (Primary Survey Model) :   3.5882  (days-weeks  )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.1980
   Biowin6 (MITI Non-Linear Model):   0.0012
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.4469
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  0.084 Pa (0.00063 mm Hg)
  Log Koa (Koawin est  ): 7.354
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  3.57E-005 
       Octanol/air (Koa) model:  5.55E-006 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.00129 
       Mackay model           :  0.00285 
       Octanol/air (Koa) model:  0.000444 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 159.0766 E-12 cm3/molecule-sec
      Half-Life =     0.067 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.807 Hrs
   Ozone Reaction:
      OVERALL Ozone Rate Constant =     1.461500 E-17 cm3/molecule-sec
      Half-Life =     0.784 Days (at 7E11 mol/cm3)
      Half-Life =     18.819 Hrs
   Fraction sorbed to airborne particulates (phi): 0.00207 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  2.087E+004
      Log Koc:  4.319 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 1.890 (BCF = 77.58)
       log Kow used: 3.36 (estimated)

 Volatilization from Water:
    Henry LC:  2.48E-006 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River:      346.3  hours   (14.43 days)
    Half-Life from Model Lake :       3900  hours   (162.5 days)

 Removal In Wastewater Treatment:
    Total removal:              10.34  percent
    Total biodegradation:        0.16  percent
    Total sludge adsorption:    10.05  percent
    Total to Air:                0.13  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.153           1.49         1000       
   Water     24.8            360          1000       
   Soil      74.3            720          1000       
   Sediment  0.829           3.24e+003    0          
     Persistence Time: 461 hr