Bookmark and Share
1 hit(s) found in 0.07 seconds
Search term: VNVDVLNLDADAGY-UHFFFAOYAF
Found by InChIKey (full match)
Please login to be able to add spectra, identifiers, links and publications.
  • Comments
  • Image
  • Spectrum
  • CIF
  • Identifier
  • Description
  • Add:
Inherent Properties, Identifiers and References
ChemSpider ID: 1235168
Empirical Formula: C17H10F3N3OS
Molecular Weight: 361.341
Nominal Mass: 361 Da
Average Mass: 361.341 Da
Monoisotopic Mass: 361.049667 Da
Systematic Name: 5-(2-furyl)-1-(4-phenylthiazol-2-yl)-3-(trifluoromethyl)pyrazole
SMILES: FC(F)(F)c3nn(c1nc(cs1)c2ccccc2)c(c3)c4occc4
InChI: InChI=1/C17H10F3N3OS/c18-17(19,20)15-9-13(14-7-4-8-24-14)23(22-15​)16-21-12(10-25-16)11-5-2-1-3-6-11/h1-10H
InChIKey: VNVDVLNLDADAGY-UHFFFAOYAF
Std. InChI: InChI=1S/C17H10F3N3OS/c18-17(19,20)15-9-13(14-7-4-8-24-14)23(22-1​5)16-21-12(10-25-16)11-5-2-1-3-6-11/h1-10H
Std. InChIKey: VNVDVLNLDADAGY-UHFFFAOYSA-N
Associated Data Sources and Commercial Suppliers Filter
Patents
PubMed Articles
Names and Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

2-[5-(2-f​uryl)-3-(​trifluoro​methyl)-1​H-pyrazol​-1-yl]-4-​phenyl-1,​3-thiazole

ACD/LogP: 5.41 # of Rule of 5 Violations: 1
ACD/LogD (pH 5.5): 5.41 ACD/LogD (pH 7.4): 5.41
ACD/BCF (pH 5.5): 7561.19 ACD/BCF (pH 7.4): 7561.19
ACD/KOC (pH 5.5): 20791.46 ACD/KOC (pH 7.4): 20791.48
#H bond acceptors: 4 #H bond donors: 0
#Freely Rotating Bonds: 3 Polar Surface Area: 72.09 Å2
Index of Refraction: 1.648 Molar Refractivity: 90.1 cm3
Molar Volume: 247.4 cm3 Polarizability: 35.72 10-24cm3
Surface Tension: 47.3 dyne/cm Density: 1.46 g/cm3
Flash Point: 265.4 °C Enthalpy of Vaporization: 78.71 kJ/mol
Boiling Point: 515.3 °C at 760 mmHg Vapour Pressure: 1E-10 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  4.68

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  464.72  (Adapted Stein & Brown method)
    Melting Pt (deg C):  196.12  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  3.35E-009  (Modified Grain method)
    Subcooled liquid VP: 2.11E-007 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  0.5294
       log Kow used: 4.68 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  0.22652 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   4.88E-013  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  3.009E-009 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  4.68  (KowWin est)
  Log Kaw used:  -10.700  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  15.380
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.1832
   Biowin2 (Non-Linear Model)     :   0.0025
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   1.9097  (months      )
   Biowin4 (Primary Survey Model) :   3.0569  (weeks       )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.2285
   Biowin6 (MITI Non-Linear Model):   0.0000
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.1000
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  2.81E-005 Pa (2.11E-007 mm Hg)
  Log Koa (Koawin est  ): 15.380
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  0.107 
       Octanol/air (Koa) model:  589 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.794 
       Mackay model           :  0.895 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =  84.9473 E-12 cm3/molecule-sec
      Half-Life =     0.126 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     1.511 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Reaction With Nitrate Radicals May Be Important!
   Fraction sorbed to airborne particulates (phi): 0.844 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  1.122E+006
      Log Koc:  6.050 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 2.906 (BCF = 805.6)
       log Kow used: 4.68 (estimated)

 Volatilization from Water:
    Henry LC:  4.88E-013 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 2.281E+009  hours   (9.503E+007 days)
    Half-Life from Model Lake : 2.488E+010  hours   (1.037E+009 days)

 Removal In Wastewater Treatment:
    Total removal:              65.05  percent
    Total biodegradation:        0.59  percent
    Total sludge adsorption:    64.46  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       1.34e-005       3.02         1000       
   Water     7.23            1.44e+003    1000       
   Soil      82              2.88e+003    1000       
   Sediment  10.8            1.3e+004     0          
     Persistence Time: 3.2e+003 hr