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Search term: LCWLYTDECDZELT-UHFFFAOYAP
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Inherent Properties, Identifiers and References
ChemSpider ID: 344676
Empirical Formula: C14H11BrN6O
Molecular Weight: 359.1807
Nominal Mass: 358 Da
Average Mass: 359.1807 Da
Monoisotopic Mass: 358.017764 Da
Systematic Name:
SMILES: Brc1ccc(cc1)N4\C=N/N3\C4=N/c2nn(CC)cc2C3=O
InChI: InChI=1/C14H11BrN6O/c1-2-19-7-11-12(18-19)17-14-20(8-16-21(14)13(​11)22)10-5-3-9(15)4-6-10/h3-8H,2H2,1H3
InChIKey: LCWLYTDECDZELT-UHFFFAOYAP
Std. InChI: InChI=1S/C14H11BrN6O/c1-2-19-7-11-12(18-19)17-14-20(8-16-21(14)13​(11)22)10-5-3-9(15)4-6-10/h3-8H,2H2,1H3
Std. InChIKey: LCWLYTDECDZELT-UHFFFAOYSA-N
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Names and Synonyms

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8-(4-Brom​ophenyl)-​2-ethyl-2​,8-dihydr​o-4H-pyra​zolo[3,4-​d][1,2,4]​triazolo[​1,5-a]pyr​imidin-4-​one

Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

ACD/LogP: 0.71 # of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 0.71 ACD/LogD (pH 7.4): 0.71
ACD/BCF (pH 5.5): 2.04 ACD/BCF (pH 7.4): 2.04
ACD/KOC (pH 5.5): 57.99 ACD/KOC (pH 7.4): 57.99
#H bond acceptors: 7 #H bond donors: 0
#Freely Rotating Bonds: 2 Polar Surface Area: 66.09 Å2
Index of Refraction: 1.811 Molar Refractivity: 86.12 cm3
Molar Volume: 199.4 cm3 Polarizability: 34.14 10-24cm3
Surface Tension: 71 dyne/cm Density: 1.8 g/cm3
Flash Point: 269 °C Enthalpy of Vaporization: 79.43 kJ/mol
Boiling Point: 521.2 °C at 760 mmHg Vapour Pressure: 5.83E-11 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  2.52

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  492.46  (Adapted Stein & Brown method)
    Melting Pt (deg C):  209.08  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  4.74E-010  (Modified Grain method)
    Subcooled liquid VP: 4.26E-008 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  38.61
       log Kow used: 2.52 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  865.79 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Hydrazines

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   2.92E-015  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  5.802E-012 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  2.52  (KowWin est)
  Log Kaw used:  -12.923  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  15.443
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.4662
   Biowin2 (Non-Linear Model)     :   0.0225
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.2694  (weeks-months)
   Biowin4 (Primary Survey Model) :   3.1760  (weeks       )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.0863
   Biowin6 (MITI Non-Linear Model):   0.0044
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.3448
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  5.68E-006 Pa (4.26E-008 mm Hg)
  Log Koa (Koawin est  ): 15.443
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  0.528 
       Octanol/air (Koa) model:  681 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.95 
       Mackay model           :  0.977 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =  77.2988 E-12 cm3/molecule-sec
      Half-Life =     0.138 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     1.660 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Fraction sorbed to airborne particulates (phi): 0.964 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  958.8
      Log Koc:  2.982 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 1.238 (BCF = 17.31)
       log Kow used: 2.52 (estimated)

 Volatilization from Water:
    Henry LC:  2.92E-015 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River:   3.8E+011  hours   (1.583E+010 days)
    Half-Life from Model Lake : 4.146E+012  hours   (1.727E+011 days)

 Removal In Wastewater Treatment:
    Total removal:               3.15  percent
    Total biodegradation:        0.10  percent
    Total sludge adsorption:     3.05  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       7.15e-007       3.32         1000       
   Water     15.8            900          1000       
   Soil      84              1.8e+003     1000       
   Sediment  0.135           8.1e+003     0          
     Persistence Time: 1.66e+003 hr