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Search term: MTKCIDPKZXGEFB-JRUCXRJDBN
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Inherent Properties, Identifiers and References
ChemSpider ID: 1372342
Empirical Formula: C23H16BrN3O3
Molecular Weight: 462.2954
Nominal Mass: 461 Da
Average Mass: 462.2954 Da
Monoisotopic Mass: 461.037496 Da
Systematic Name: (E)-3-(4-bromo-3-nitro-phenyl)-N-[4-(5-methyl-1,3-benzoxazol-2-yl​)phenyl]prop-2-en-1-imine
SMILES: [O-][N+](=O)c1c(Br)ccc(c1)\C=C\C=N\c4ccc(c2nc3cc(ccc3o2)C)cc4
InChI: InChI=1/C23H16BrN3O3/c1-15-4-11-22-20(13-15)26-23(30-22)17-6-8-18​(9-7-17)25-12-2-3-16-5-10-19(24)21(14-16)27(28)29/h2-14H,1H3/b3-2​+,25-12+
InChIKey: MTKCIDPKZXGEFB-JRUCXRJDBN
Std. InChI: InChI=1S/C23H16BrN3O3/c1-15-4-11-22-20(13-15)26-23(30-22)17-6-8-1​8(9-7-17)25-12-2-3-16-5-10-19(24)21(14-16)27(28)29/h2-14H,1H3/b3-​2+,25-12+
Std. InChIKey: MTKCIDPKZXGEFB-JRUCXRJDSA-N
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Names and Synonyms

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2-{4-[(3-​{4-bromo-​3-nitroph​enyl}-2-p​ropenylid​ene)amino​]phenyl}-​5-methyl-​1,3-benzo​xazole

Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

ACD/LogP: 7.87 # of Rule of 5 Violations: 1
ACD/LogD (pH 5.5): 7.87 ACD/LogD (pH 7.4): 7.87
ACD/BCF (pH 5.5): 565471.13 ACD/BCF (pH 7.4): 565848.06
ACD/KOC (pH 5.5): 456103.44 ACD/KOC (pH 7.4): 456407.5
#H bond acceptors: 6 #H bond donors: 0
#Freely Rotating Bonds: 5 Polar Surface Area: 84.21 Å2
Index of Refraction: 1.661 Molar Refractivity: 118.87 cm3
Molar Volume: 321.5 cm3 Polarizability: 47.12 10-24cm3
Surface Tension: 52 dyne/cm Density: 1.43 g/cm3
Flash Point: 304 °C Enthalpy of Vaporization: 83.44 kJ/mol
Boiling Point: 579.1 °C at 760 mmHg Vapour Pressure: 8.43E-13 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  6.71

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  578.23  (Adapted Stein & Brown method)
    Melting Pt (deg C):  249.14  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  9.96E-013  (Modified Grain method)
    Subcooled liquid VP: 2.72E-010 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  0.0009383
       log Kow used: 6.71 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  0.0033685 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Schiff Bases

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   1.22E-012  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  6.457E-010 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  6.71  (KowWin est)
  Log Kaw used:  -10.302  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  17.012
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.1667
   Biowin2 (Non-Linear Model)     :   0.0008
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   1.7971  (months      )
   Biowin4 (Primary Survey Model) :   2.8503  (weeks       )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.5987
   Biowin6 (MITI Non-Linear Model):   0.0000
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model): -1.0170
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  3.63E-008 Pa (2.72E-010 mm Hg)
  Log Koa (Koawin est  ): 17.012
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  82.7 
       Octanol/air (Koa) model:  2.52E+004 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1 
       Mackay model           :  1 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =  80.2724 E-12 cm3/molecule-sec [Cis-isomer]
      OVERALL OH Rate Constant =  87.8724 E-12 cm3/molecule-sec [Trans-isomer]
      Half-Life =    1.599 Hrs (12-hr day; 1.5E6 OH/cm3) [Cis-isomer]
      Half-Life =    1.461 Hrs (12-hr day; 1.5E6 OH/cm3) [Trans-isomer]
   Ozone Reaction:
      OVERALL Ozone Rate Constant =     6.825000 E-17 cm3/molecule-sec [Cis-]
      OVERALL Ozone Rate Constant =    13.650000 E-17 cm3/molecule-sec [Trans-]
      Half-Life =     4.030 Hrs (at 7E11 mol/cm3) [Cis-isomer]
      Half-Life =     2.015 Hrs (at 7E11 mol/cm3) [Trans-isomer]
   Fraction sorbed to airborne particulates (phi): 1 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  4.976E+007
      Log Koc:  7.697 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 4.469 (BCF = 2.945e+004)
       log Kow used: 6.71 (estimated)

 Volatilization from Water:
    Henry LC:  1.22E-012 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 1.032E+009  hours   (4.299E+007 days)
    Half-Life from Model Lake : 1.126E+010  hours   (4.69E+008 days)

 Removal In Wastewater Treatment:
    Total removal:              93.66  percent
    Total biodegradation:        0.78  percent
    Total sludge adsorption:    92.89  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.00806         1.78         1000       
   Water     1.57            1.44e+003    1000       
   Soil      38.5            2.88e+003    1000       
   Sediment  59.9            1.3e+004     0          
     Persistence Time: 5.21e+003 hr