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Search term: CNZKEPDFYLMHMH-VHXPQNKSBB
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Inherent Properties, Identifiers and References
ChemSpider ID: 1611522
Empirical Formula: C23H25N3O3S2
Molecular Weight: 455.5929
Nominal Mass: 455 Da
Average Mass: 455.5929 Da
Monoisotopic Mass: 455.133732 Da
Systematic Name: (NZ)-4-(diallylsulfamoyl)-N-(3-ethyl-6-methyl-1,3-benzothiazol-2-​ylidene)benzamide
SMILES: O=S(=O)(N(C\C=C)C\C=C)c1ccc(cc1)C(=O)/N=C3\Sc2cc(ccc2N3CC)C
InChI: InChI=1/C23H25N3O3S2/c1-5-14-25(15-6-2)31(28,29)19-11-9-18(10-12-​19)22(27)24-23-26(7-3)20-13-8-17(4)16-21(20)30-23/h5-6,8-13,16H,1​-2,7,14-15H2,3-4H3/b24-23-
InChIKey: CNZKEPDFYLMHMH-VHXPQNKSBB
Std. InChI: InChI=1S/C23H25N3O3S2/c1-5-14-25(15-6-2)31(28,29)19-11-9-18(10-12​-19)22(27)24-23-26(7-3)20-13-8-17(4)16-21(20)30-23/h5-6,8-13,16H,​1-2,7,14-15H2,3-4H3/b24-23-
Std. InChIKey: CNZKEPDFYLMHMH-VHXPQNKSSA-N
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ACD/LogP: 6.01 # of Rule of 5 Violations: 1
ACD/LogD (pH 5.5): 6.01 ACD/LogD (pH 7.4): 6.01
ACD/BCF (pH 5.5): 21741.09 ACD/BCF (pH 7.4): 21741.09
ACD/KOC (pH 5.5): 44280.41 ACD/KOC (pH 7.4): 44280.41
#H bond acceptors: 6 #H bond donors: 0
#Freely Rotating Bonds: 9 Polar Surface Area: 103.73 Å2
Index of Refraction: 1.613 Molar Refractivity: 129.54 cm3
Molar Volume: 371.9 cm3 Polarizability: 51.35 10-24cm3
Surface Tension: 46.6 dyne/cm Density: 1.22 g/cm3
Flash Point: 327.4 °C Enthalpy of Vaporization: 91.6 kJ/mol
Boiling Point: 617.7 °C at 760 mmHg Vapour Pressure: 3.45E-15 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  5.33

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  597.48  (Adapted Stein & Brown method)
    Melting Pt (deg C):  258.13  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  2.44E-013  (Modified Grain method)
    Subcooled liquid VP: 8.58E-011 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  0.003429
       log Kow used: 5.33 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  0.030206 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   1.52E-014  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  4.266E-011 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  5.33  (KowWin est)
  Log Kaw used:  -12.207  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  17.537
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.5853
   Biowin2 (Non-Linear Model)     :   0.0530
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.1175  (months      )
   Biowin4 (Primary Survey Model) :   3.1219  (weeks       )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.3585
   Biowin6 (MITI Non-Linear Model):   0.0003
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model): -0.6464
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  1.14E-008 Pa (8.58E-011 mm Hg)
  Log Koa (Koawin est  ): 17.537
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  262 
       Octanol/air (Koa) model:  8.45E+004 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1 
       Mackay model           :  1 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 189.6786 E-12 cm3/molecule-sec
      Half-Life =     0.056 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.677 Hrs
   Ozone Reaction:
      OVERALL Ozone Rate Constant =     2.400000 E-17 cm3/molecule-sec
      Half-Life =     0.477 Days (at 7E11 mol/cm3)
      Half-Life =     11.460 Hrs
   Fraction sorbed to airborne particulates (phi): 1 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  2.111E+006
      Log Koc:  6.325 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 3.404 (BCF = 2535)
       log Kow used: 5.33 (estimated)

 Volatilization from Water:
    Henry LC:  1.52E-014 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 8.222E+010  hours   (3.426E+009 days)
    Half-Life from Model Lake : 8.969E+011  hours   (3.737E+010 days)

 Removal In Wastewater Treatment:
    Total removal:              85.72  percent
    Total biodegradation:        0.73  percent
    Total sludge adsorption:    84.99  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.000907        1.21         1000       
   Water     4.85            1.44e+003    1000       
   Soil      65.4            2.88e+003    1000       
   Sediment  29.7            1.3e+004     0          
     Persistence Time: 3.9e+003 hr