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Search term: JKMVYIRIDKEFSM-UHFFFAOYAM
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Inherent Properties, Identifiers and References
ChemSpider ID: 961058
Empirical Formula: C23H16N2O5
Molecular Weight: 400.3835
Nominal Mass: 400 Da
Average Mass: 400.3835 Da
Monoisotopic Mass: 400.105922 Da
Systematic Name: [2-methyl-3-(1-methylbenzimidazol-2-yl)-4-oxo-chromen-7-yl] furan​-2-carboxylate
SMILES: O=C(Oc4ccc1c(O/C(=C(\C1=O)c2nc3ccccc3n2C)C)c4)c5occc5
InChI: InChI=1/C23H16N2O5/c1-13-20(22-24-16-6-3-4-7-17(16)25(22)2)21(26)​15-10-9-14(12-19(15)29-13)30-23(27)18-8-5-11-28-18/h3-12H,1-2H3
InChIKey: JKMVYIRIDKEFSM-UHFFFAOYAM
Std. InChI: InChI=1S/C23H16N2O5/c1-13-20(22-24-16-6-3-4-7-17(16)25(22)2)21(26​)15-10-9-14(12-19(15)29-13)30-23(27)18-8-5-11-28-18/h3-12H,1-2H3
Std. InChIKey: JKMVYIRIDKEFSM-UHFFFAOYSA-N
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Names and Synonyms

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2-methyl-​3-(1-meth​yl-1H-ben​zimidazol​-2-yl)-4-​oxo-4H-ch​romen-7-y​l 2-furoa​te

2-methyl-​3-(1-meth​ylbenzimi​dazol-2-y​l)-4-oxoc​hromen-7-​yl furan-​2-carboxy​late

Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

ACD/LogP: 4.29 # of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 4.2 ACD/LogD (pH 7.4): 4.29
ACD/BCF (pH 5.5): 879.51 ACD/BCF (pH 7.4): 1073.31
ACD/KOC (pH 5.5): 4208.81 ACD/KOC (pH 7.4): 5136.23
#H bond acceptors: 7 #H bond donors: 0
#Freely Rotating Bonds: 4 Polar Surface Area: 83.56 Å2
Index of Refraction: 1.676 Molar Refractivity: 108.31 cm3
Molar Volume: 287.8 cm3 Polarizability: 42.93 10-24cm3
Surface Tension: 52.8 dyne/cm Density: 1.39 g/cm3
Flash Point: 312.1 °C Enthalpy of Vaporization: 88.35 kJ/mol
Boiling Point: 592.4 °C at 760 mmHg Vapour Pressure: 5.23E-14 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  4.02

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  591.59  (Adapted Stein & Brown method)
    Melting Pt (deg C):  255.38  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  3.75E-013  (Modified Grain method)
    Subcooled liquid VP: 1.22E-010 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  1.127
       log Kow used: 4.02 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  0.57059 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Esters
       Vinyl/Allyl Ketones
       Vinyl/Allyl Ethers
       Imidazoles

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   1.95E-013  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  1.753E-013 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  4.02  (KowWin est)
  Log Kaw used:  -11.098  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  15.118
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.8698
   Biowin2 (Non-Linear Model)     :   0.9608
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.3740  (weeks-months)
   Biowin4 (Primary Survey Model) :   3.5539  (days-weeks  )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.2607
   Biowin6 (MITI Non-Linear Model):   0.0395
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model): -0.3194
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  1.63E-008 Pa (1.22E-010 mm Hg)
  Log Koa (Koawin est  ): 15.118
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  184 
       Octanol/air (Koa) model:  322 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1 
       Mackay model           :  1 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 129.7542 E-12 cm3/molecule-sec
      Half-Life =     0.082 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.989 Hrs
   Ozone Reaction:
      OVERALL Ozone Rate Constant =    68.249992 E-17 cm3/molecule-sec
      Half-Life =     0.017 Days (at 7E11 mol/cm3)
      Half-Life =     24.179 Min
   Reaction With Nitrate Radicals May Be Important!
   Fraction sorbed to airborne particulates (phi): 1 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  1.52E+004
      Log Koc:  4.182 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
  Total Kb for pH > 8 at 25 deg C :  5.843E+000  L/mol-sec
  Kb Half-Life at pH 8:       1.373  days   
  Kb Half-Life at pH 7:      13.730  days   

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 1.554 (BCF = 35.81)
       log Kow used: 4.02 (estimated)

 Volatilization from Water:
    Henry LC:  1.95E-013 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 6.008E+009  hours   (2.503E+008 days)
    Half-Life from Model Lake : 6.554E+010  hours   (2.731E+009 days)

 Removal In Wastewater Treatment:
    Total removal:              30.99  percent
    Total biodegradation:        0.33  percent
    Total sludge adsorption:    30.66  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.00793         0.335        1000       
   Water     14.2            900          1000       
   Soil      82.2            1.8e+003     1000       
   Sediment  3.52            8.1e+003     0          
     Persistence Time: 1.36e+003 hr