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Search term: ZMDILJFQXHIQHP-UHFFFAOYAO
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Inherent Properties, Identifiers and References
ChemSpider ID: 1230597
Empirical Formula: C22H16BrNO4S
Molecular Weight: 470.3357
Nominal Mass: 469 Da
Average Mass: 470.3357 Da
Monoisotopic Mass: 468.998333 Da
Systematic Name: N-(4-bromo-9-oxo-7,8-dihydro-6H-dibenzofuran-2-yl)naphthalene-2-s​ulfonamide
SMILES: O=S(=O)(c2cc1ccccc1cc2)Nc5cc4c(oc3c4C(=O)CCC3)c(Br)c5
InChI: InChI=1/C22H16BrNO4S/c23-18-12-15(11-17-21-19(25)6-3-7-20(21)28-2​2(17)18)24-29(26,27)16-9-8-13-4-1-2-5-14(13)10-16/h1-2,4-5,8-12,2​4H,3,6-7H2
InChIKey: ZMDILJFQXHIQHP-UHFFFAOYAO
Std. InChI: InChI=1S/C22H16BrNO4S/c23-18-12-15(11-17-21-19(25)6-3-7-20(21)28-​22(17)18)24-29(26,27)16-9-8-13-4-1-2-5-14(13)10-16/h1-2,4-5,8-12,​24H,3,6-7H2
Std. InChIKey: ZMDILJFQXHIQHP-UHFFFAOYSA-N
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

ACD/LogP: 5.86 # of Rule of 5 Violations: 1
ACD/LogD (pH 5.5): 5.83 ACD/LogD (pH 7.4): 5.04
ACD/BCF (pH 5.5): 15665.64 ACD/BCF (pH 7.4): 2557.41
ACD/KOC (pH 5.5): 34314.12 ACD/KOC (pH 7.4): 5601.76
#H bond acceptors: 5 #H bond donors: 1
#Freely Rotating Bonds: 2 Polar Surface Area: 75.97 Å2
Index of Refraction: 1.733 Molar Refractivity: 115.83 cm3
Molar Volume: 289 cm3 Polarizability: 45.92 10-24cm3
Surface Tension: 69.2 dyne/cm Density: 1.626 g/cm3
Flash Point: 349.7 °C Enthalpy of Vaporization: 96.42 kJ/mol
Boiling Point: 654.6 °C at 760 mmHg Vapour Pressure: 5.15E-17 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  5.85

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  612.43  (Adapted Stein & Brown method)
    Melting Pt (deg C):  265.12  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  8.13E-014  (Modified Grain method)
    Subcooled liquid VP: 3.49E-011 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  0.0008671
       log Kow used: 5.85 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  0.0083622 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   1.04E-012  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  5.803E-011 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  5.85  (KowWin est)
  Log Kaw used:  -10.371  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  16.221
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.4748
   Biowin2 (Non-Linear Model)     :   0.0054
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   1.9264  (months      )
   Biowin4 (Primary Survey Model) :   2.9249  (weeks       )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.3449
   Biowin6 (MITI Non-Linear Model):   0.0007
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model): -0.7765
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  4.65E-009 Pa (3.49E-011 mm Hg)
  Log Koa (Koawin est  ): 16.221
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  645 
       Octanol/air (Koa) model:  4.08E+003 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1 
       Mackay model           :  1 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 113.4119 E-12 cm3/molecule-sec
      Half-Life =     0.094 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     1.132 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Fraction sorbed to airborne particulates (phi): 1 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  7.542E+005
      Log Koc:  5.878 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 2.965 (BCF = 922.2)
       log Kow used: 5.85 (estimated)

 Volatilization from Water:
    Henry LC:  1.04E-012 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 1.221E+009  hours   (5.087E+007 days)
    Half-Life from Model Lake : 1.332E+010  hours   (5.55E+008 days)

 Removal In Wastewater Treatment:
    Total removal:              91.39  percent
    Total biodegradation:        0.76  percent
    Total sludge adsorption:    90.63  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.0221          2.26         1000       
   Water     3.39            1.44e+003    1000       
   Soil      43              2.88e+003    1000       
   Sediment  53.5            1.3e+004     0          
     Persistence Time: 3.8e+003 hr