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Search term: AUQFLDJUIXQQFT-UHFFFAOYAA
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Inherent Properties, Identifiers and References
ChemSpider ID: 2848214
Empirical Formula: C28H24N2O3S
Molecular Weight: 468.5668
Nominal Mass: 468 Da
Average Mass: 468.5668 Da
Monoisotopic Mass: 468.150763 Da
Systematic Name: 4-(4-hydroxy-3-methoxy-phenyl)-2-(1-naphthylmethylsulfanyl)-5-oxo​-4,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile
SMILES: O=C5\C3=C(\NC(\SCc2c1ccccc1ccc2)=C(\C#N)C3c4ccc(O)c(OC)c4)CCC5
InChI: InChI=1/C28H24N2O3S/c1-33-25-14-18(12-13-23(25)31)26-21(15-29)28(​30-22-10-5-11-24(32)27(22)26)34-16-19-8-4-7-17-6-2-3-9-20(17)19/h​2-4,6-9,12-14,26,30-31H,5,10-11,16H2,1H3
InChIKey: AUQFLDJUIXQQFT-UHFFFAOYAA
Std. InChI:
Std. InChIKey: -
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ACD/LogP: 4.03 # of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 4.03 ACD/LogD (pH 7.4): 4.02
ACD/BCF (pH 5.5): 675.66 ACD/BCF (pH 7.4): 672.75
ACD/KOC (pH 5.5): 3690.73 ACD/KOC (pH 7.4): 3674.85
#H bond acceptors: 5 #H bond donors: 2
#Freely Rotating Bonds: 6 Polar Surface Area: 87.86 Å2
Index of Refraction: 1.714 Molar Refractivity: 134.37 cm3
Molar Volume: 342.1 cm3 Polarizability: 53.27 10-24cm3
Surface Tension: 70.5 dyne/cm Density: 1.36 g/cm3
Flash Point: 382.7 °C Enthalpy of Vaporization: 107.42 kJ/mol
Boiling Point: 709.2 °C at 760 mmHg Vapour Pressure: 8.85E-21 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  4.35

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  681.17  (Adapted Stein & Brown method)
    Melting Pt (deg C):  297.23  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  2.54E-017  (Modified Grain method)
    Subcooled liquid VP: 2.75E-014 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  1.213
       log Kow used: 4.35 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  2.5857 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Aliphatic Amines
       Allylic/Vinyl Nitriles
       Phenols
       Vinyl/Allyl Ketones

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   2.36E-018  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  1.291E-017 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  4.35  (KowWin est)
  Log Kaw used:  -16.016  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  20.366
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   1.2945
   Biowin2 (Non-Linear Model)     :   0.9955
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.0067  (months      )
   Biowin4 (Primary Survey Model) :   3.1758  (weeks       )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :  -0.1234
   Biowin6 (MITI Non-Linear Model):   0.0018
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model): -0.6024
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  3.67E-012 Pa (2.75E-014 mm Hg)
  Log Koa (Koawin est  ): 20.366
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  8.18E+005 
       Octanol/air (Koa) model:  5.7E+007 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1 
       Mackay model           :  1 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 240.1404 E-12 cm3/molecule-sec
      Half-Life =     0.045 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.534 Hrs
   Ozone Reaction:
      OVERALL Ozone Rate Constant =     7.450625 E-17 cm3/molecule-sec
      Half-Life =     0.154 Days (at 7E11 mol/cm3)
      Half-Life =      3.691 Hrs
   Reaction With Nitrate Radicals May Be Important!
   Fraction sorbed to airborne particulates (phi): 1 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  2.354E+006
      Log Koc:  6.372 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 2.649 (BCF = 446.1)
       log Kow used: 4.35 (estimated)

 Volatilization from Water:
    Henry LC:  2.36E-018 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River:  5.37E+014  hours   (2.238E+013 days)
    Half-Life from Model Lake : 5.858E+015  hours   (2.441E+014 days)

 Removal In Wastewater Treatment:
    Total removal:              47.97  percent
    Total biodegradation:        0.46  percent
    Total sludge adsorption:    47.51  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.000739        0.829        1000       
   Water     8.12            1.44e+003    1000       
   Soil      86.2            2.88e+003    1000       
   Sediment  5.64            1.3e+004     0          
     Persistence Time: 2.96e+003 hr