Copyright©2008 Antony Williams
The DailyMed website is a valuable website when it comes to chemical names, trade names, drug names and chemical structures.What is interesting is the quality of the information on the website. We were originally interested in using the website to expand our dictionary of drug names and associated chemical structures and exercising our text-mining tools to recognize chemical structures. In order to test our text-mining capabilities we had to examine every record for accuracy and appropriateness and to tune the algorithms. This amounted to over 3000 records. During this process we were able to review every chemical structure diagram and the appropriateness of these diagrams. As part of the process we were able to build a highly validated dataset of chemical structures and their chemical/trade/drug names. These will be exposed on ChemSpider in the near future.
For now lets examine the quality of information on Daily Med.
The website is advertised as:
“DailyMed provides high quality information about marketed drugs. This information includes FDA approved labels (package inserts). This Web site provides health information providers and the public with a standard, comprehensive, up-to-date, look-up and download resource of medication content and labeling as found in medication package inserts. ”
So, what type of materials can we find on Daily Med?
Look at Soltamox here. What do you think about the chemical structure image below? Do you think that was drawn with a structure drawing software package?
My favorite “not drawn by a chemist” chemical structure is the one for cefobid shown below.
Many chemical structures on DailyMed are imperfect. What is quite shocking is that many of these are not even drawn with structure drawing packages. There are other issues…more to come.
COMMENT: DailyMed is a delivery vehicle for content provided by vendors (I believe). The site is a valuable public service and is applauded. The hope is the work that we are doing on Daily Med will be of similar value and might encourage that some of the labels will be “cleaned up”Stumble it!