• Sciencebase.com on Facebook
  • Blogroll

Archive for September, 2007

Droning On About Bee Chemistry

Posted by David Bradley on September 6th, 2007

 9-oxo-2-decenoic acid structureNot spiders, but bees. Researchers at the University of Illinois Urbana-Champaign have identified an odorant receptor that allows male bee drones to find a queen in flight. The receptor is present on the male antennae and can detect an available queen up to 60 metres away, which is quite a feat in chemical detection. This is the first time an odorant receptor has been linked to a specific pheromone in honey bees.

Droning on about bee chemistry.

Painkiller Slows Bone Growth

Posted by David Bradley on September 4th, 2007

Paracetamol structure, TylenolA press release just in announced that “Paracetamol, one of most used analgesics, could slow down bone growth”. In vitro tests apparently demonstrated that the compound slows bone regeneration in the proverbial test-tube.

More on painkiller slows bone growth

The press release writer missed a serious trick in using the word paracetamol throughout and not mentioning some of the proprietary formulations of the analgesic, which include the far more familiar names Tylenol, Acetaminofen, Acetaminophen, and Amadil, it may be picked up by the US media with that name, but I suspect a headline mentioning Tylenol would be a far stronger grab.

Olga García Martínez of the Departamento de Enfermeria at the University of Granada and colleagues based their analysis on several clinical processes in which accelerating bone growth is required. “Certain anti-inflammatories such as paracetamol should be cautiously taken, especially in situations in which require a rapid bone tissue regeneration, such as after placement of a prosthesis or dental implant is needed,” she says. Other anti-inflammatories that have no such effect on bone growth should be used instead.

The research has not been confirmed in people yet, but somehow the tests on isolated osteoblasts are taken as definitive evidence that the drug will slow bone regeneration in vivo.