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Extracellular vesicle-mediated co-delivery of TRAIL and dinaciclib for targeted therapy of resistant tumors . Changhong Ke, Huan Hou, Kui Su, Chaohong Huang, Qian Yuan, Shuyi Li, Jianwu Sun, Yue Lin, Chuanbin Wu, Yu Zhao, Zhengqiang Yuan
, Biomater. Sci.
, 2022
, 10
, 1498
CDK9 inhibitors in cancer research . Zhi Huang, Tianqi Wang, Cheng Wang, Yan Fan
, RSC Med. Chem.
, 2022
, 13
, 688
Small molecule inhibitors in pancreatic cancer . Jufeng Sun, Cecilia C. Russell, Christopher J. Scarlett, Adam McCluskey
, RSC Med. Chem.
, 2020
, 11
, 164
An in silico exploration of the interaction mechanism of pyrazolo[1,5-a ]pyrimidine type CDK2 inhibitors . Yan Li, Weimin Gao, Feng Li, Jinghui Wang, Jingxiao Zhang, Yinfeng Yang, Shuwei Zhang, Ling Yang
, Mol. BioSyst.
, 2013
, 9
, 2266
Synthesis and biological evaluation of chalcone-linked pyrazolo[1,5-a ]pyrimidines as potential anticancer agents . Chandrakant Bagul, Garikapati Koteswara Rao, Venkata Krishna Kanth Makani, Jaki R. Tamboli, Manika Pal-Bhadra, Ahmed Kamal
, Med. Chem. Commun.
, 2017
, 8
, 1810
High-throughput drug target discovery using a fully automated proteomics sample preparation platform . Qiong Wu, Jiangnan Zheng, Xintong Sui, Changying Fu, Xiaozhen Cui, Bin Liao, Hongchao Ji, Yang Luo, An He, Xue Lu, Xinyue Xue, Chris Soon Heng Tan, Ruijun Tian
, Chem. Sci.
, 2024
, 15
, 2833
Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action . Fatma A. M. Mohamed, Saleha Y. M. Alakilli, Eman Fawzy El Azab, Faris A. M. Baawad, Esraa Ibrahim A. Shaaban, Heba Abu Alrub, Omnia Hendawy, Hesham A. M. Gomaa, Adel G. Bakr, Mostafa H. Abdelrahman, Laurent Trembleau, Anber F. Mohammed, Bahaa G. M. Youssif
, RSC Med. Chem.
, 2023
, 14
, 734
Research progress of anticancer drugs targeting CDK12 . Zhijia Yan, Yongli Du, Haibin Zhang, Yong Zheng, Huiting Lv, Ning Dong, Fang He
, RSC Med. Chem.
, 2023
, 14
, 1629
Novel tacrine derivatives as potential CDK9 inhibitors with low cholinesterase inhibitory properties: design, synthesis, and biological evaluation . Wenwu Liu, Yaoguang Huang, Limeng Wu, Wenjie Liu, Xiaowen Jiang, Zihua Xu, Qingchun Zhao
, New J. Chem.
, 2022
, 46
, 19342
Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9 . Carl S. Rye, Nicola E. A. Chessum, Scott Lamont, Kurt G. Pike, Paul Faulder, Julie Demeritt, Paul Kemmitt, Julie Tucker, Lorenzo Zani, Matthew D. Cheeseman, Rosie Isaac, Louise Goodwin, Joanna Boros, Florence Raynaud, Angela Hayes, Alan T. Henley, Emmanuel de Billy, Christopher J. Lynch, Swee Y. Sharp, Robert te Poele, Lisa O’ Fee, Kevin M. Foote, Stephen Green, Paul Workman, Keith Jones
, Med. Chem. Commun.
, 2016
, 7
, 1580