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Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitors. Richard J. R. Elliott, Ashley Jarvis, Mohan B. Rajasekaran, Malini Menon, Leandra Bowers, Ray Boffey, Melanie Bayford, Stuart Firth-Clark, Rebekah Key, Rehan Aqil, Stewart B. Kirton, Dan Niculescu-Duvaz, Laura Fish, Filipa Lopes, Robert McLeary, Ines Trindade, Elisenda Vendrell, Felix Munkonge, Rod Porter, Trevor Perrior, Caroline Springer, Antony W. Oliver, Laurence H. Pearl, Alan Ashworth, Christopher J. Lord
, Med. Chem. Commun.
, 2015
, 6
, 1687