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- 20-O-IngenolEZ, a catalytic topoisomerase II inhibitor, specifically inhibits cell proliferation and induces double-strand DNA breaks in BLM
-/-cells. Manami Watanabe, Yuta Kamada, Khosuke Miyazaki, Shoko Mizoguchi, Keiichi Matsuzaki, Susumu Kitanaka, Shohei Miyata
, Med. Chem. Commun.
, 2011
, 2
, 824
- Gelation of the genome by topoisomerase II targeting anticancer agents. Yun Soo Kim, Binu Kundukad, Abdollah Allahverdi, Lars Nordensköld, Patrick S. Doyle, Johan R. C. van der Maarel
, Soft Matter
, 2013
, 9
, 1656
- Target identification of small molecules based on chemical biology approaches. Yushi Futamura, Makoto Muroi, Hiroyuki Osada
, Mol. BioSyst.
, 2013
, 9
, 897