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- Rapid synthesis of pomalidomide-conjugates for the development of protein degrader libraries. Duncan K. Brownsey, Ben C. Rowley, Evgueni Gorobets, Benjamin S. Gelfand, Darren J. Derksen
, Chem. Sci.
, 2021
, 12
, 4519
- Shifting the paradigm in treating multi-factorial diseases: polypharmacological co-inhibitors of HDAC6. Alexandria M. Chan, Steven Fletcher
, RSC Med. Chem.
, 2021
, 12
, 178
- Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders. Junichi Yamamoto, Takumi Ito, Yuki Yamaguchi, Hiroshi Handa
, Chem. Soc. Rev.
, 2022
, 51
, 6234
- Utilising the intrinsic fluorescence of pomalidomide for imaging applications. Duncan K. Brownsey, Christopher J. Gafuik, Dae-Sun Kim, Leonie O’Sullivan, Evgueni Gorobets, Samuel Krukowski, Madison Turk, Craig N. Jenne, Douglas J. Mahoney, Darren J. Derksen
, Chem. Commun.
, 2023
, 59
, 14532
- Selective degradation-inducing probes for studying cereblon (CRBN) biology. Chelsea E. Powell, Guangyan Du, Jonathan W. Bushman, Zhixiang He, Tinghu Zhang, Eric S. Fischer, Nathanael S. Gray
, RSC Med. Chem.
, 2021
, 12
, 1381
- 3-Aminophthalic acid, a new cereblon ligand for targeted protein degradation by O’PROTAC. Yuqian Yan, Jingwei Shao, Donglin Ding, Yunqian Pan, Phuc Tran, Wei Yan, Zhengyu Wang, Hong-yu Li, Haojie Huang
, Chem. Commun.
, 2022
, 58
, 2383
- Structure–activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase. Yuki Murakami, Hinata Osawa, Takashi Kurohara, Yuta Yanase, Takahito Ito, Hidetomo Yokoo, Norihito Shibata, Mikihiko Naito, Kosuke Aritake, Yosuke Demizu
, RSC Med. Chem.
, 2022
, 13
, 1495
- E3 ligase ligand chemistries: from building blocks to protein degraders. Izidor Sosič, Aleša Bricelj, Christian Steinebach
, Chem. Soc. Rev.
, 2022
, 51
, 3487
- Chemistries of bifunctional PROTAC degraders. Chaoguo Cao, Ming He, Liguo Wang, Yuna He, Yu Rao
, Chem. Soc. Rev.
, 2022
, 51
, 7066
- Chemically induced degradation of epigenetic targets. Md Kabir, Xufen Yu, H. Ümit Kaniskan, Jian Jin
, Chem. Soc. Rev.
, 2023
, 52
, 4313