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- Discovery of imidazo[1,2-b]pyridazine-containing TAK1 kinase inhibitors with excellent activities against multiple myeloma. Desmond Akwata, Allison L. Kempen, Jones Lamptey, Neetu Dayal, Nickolas R. Brauer, Herman O. Sintim
, RSC Med. Chem.
, 2024
, 15
, 178
- Microwave-assisted synthesis in water: first one-pot synthesis of a novel class of polysubstituted benzo[4,5]imidazo[1,2-b]pyridazines via intramolecular SNAr. Haider Behbehani, Hamada Mohamed Ibrahim
, RSC Adv.
, 2015
, 5
, 89226
- Advances in direct C–H arylation of 5,5- 6,5- and 6,6-fused-heterocycles containing heteroatoms (N, O, S). Saïd El Kazzouli, Jamal Koubachi, Nabil El Brahmi, Gérald Guillaumet
, RSC Adv.
, 2015
, 5
, 15292
- Antiplasmodial imidazopyridazines: structure–activity relationship studies lead to the identification of analogues with improved solubility and hERG profiles. Peter Mubanga Cheuka, Nina Lawrence, Dale Taylor, Sergio Wittlin, Kelly Chibale
, Med. Chem. Commun.
, 2018
, 9
, 1733
- Identification of imidazo[1,2-b]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling. R. Moslin, D. Gardner, J. Santella, Y. Zhang, J. V. Duncia, C. Liu, J. Lin, J. S. Tokarski, J. Strnad, D. Pedicord, J. Chen, Y. Blat, A. Zupa-Fernandez, L. Cheng, H. Sun, C. Chaudhry, C. Huang, C. D'Arienzo, J. S. Sack, J. K. Muckelbauer, C. Chang, J. Tredup, D. Xie, N. Aranibar, J. R. Burke, P. H. Carter, D. S. Weinstein
, Med. Chem. Commun.
, 2017
, 8
, 700
- Iodine-catalyzed regioselective sulfenylation of imidazoheterocycles in PEG400. Marie-Aude Hiebel, Sabine Berteina-Raboin
, Green Chem.
, 2015
, 17
, 937
- Development of subnanomolar radiofluorinated (2-pyrrolidin-1-yl)imidazo[1,2-b]pyridazine pan-Trk inhibitors as candidate PET imaging probes. Vadim Bernard-Gauthier, Justin J. Bailey, Arturo Aliaga, Alexey Kostikov, Pedro Rosa-Neto, Melinda Wuest, Garrett M. Brodeur, Barry J. Bedell, Frank Wuest, Ralf Schirrmacher
, Med. Chem. Commun.
, 2015
, 6
, 2184
- Exploring the untapped pharmacological potential of imidazopyridazines. M. Shaheer Malik, Hossa F. Alshareef, Khalid A. Alfaidi, Hissana Ather, Zainularifeen Abduljaleel, Essam M. Hussein, Ziad Moussa, Saleh A. Ahmed
, RSC Adv.
, 2024
, 14
, 3972
- 1,3-Dipolar cycloaddition of 2-diazopropane to imidazo[1,2-b]pyridazine derivatives. The synthesis of imidazo[1,2-b]pyrazolo[4,3-d]pyridazines derivatives of a novel heterocyclic system. Branko Stanovnik, Marko Kupper, Miha Tišler, Ivan Leban, Ljubo Golič
, J. Chem. Soc., Chem. Commun.
, 1984
, 268
- Electrochemical sulfonylation of imidazoheterocycles under batch and continuous flow conditions. Elise Leclercq, Maxime Boddaert, Mathieu Beaucamp, Maël Penhoat, Laëtitia Chausset-Boissarie
, Org. Biomol. Chem.
, 2021
, 19
, 9379