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- Stabilised G protein-coupled receptors in structure-based drug design: a case study with adenosine A2A receptor. Stephen P. Andrews, Benjamin Tehan
, Med. Chem. Commun.
, 2013
, 4
, 52
- Single molecule binding of a ligand to a G-protein-coupled receptor in real time using fluorescence correlation spectroscopy, rendered possible by nano-encapsulation in styrene maleic acid lipid particles. Rachael L. Grime, Joelle Goulding, Romez Uddin, Leigh A. Stoddart, Stephen J. Hill, David R. Poyner, Stephen J. Briddon, Mark Wheatley
, Nanoscale
, 2020
, 12
, 11518
- Incorporating QM and solvation into docking for applications to GPCR targets. Minsup Kim, Art E. Cho
, Phys. Chem. Chem. Phys.
, 2016
, 18
, 28281
- New substituted 9-propyladenine derivatives as A2A
adenosine receptor antagonists. C. Lambertucci, M. Buccioni, D. Dal Ben, S. Kachler, G. Marucci, A. Spinaci, A. Thomas, K.-N. Klotz, R. Volpini
, Med. Chem. Commun.
, 2015
, 6
, 963
- Substituted pyrazolo[3,4-b]pyridines as human A1adenosine antagonists: Developments in understanding the receptor stereoselectivity. Tiziano Tuccinardi, Alessandra Tania Zizzari, Chiara Brullo, Simona Daniele, Francesca Musumeci, Silvia Schenone, Maria Letizia Trincavelli, Claudia Martini, Adriano Martinelli, Gianluca Giorgi, Maurizio Botta
, Org. Biomol. Chem.
, 2011
, 9
, 4448
- Sulforaphane attenuates glycoprotein VI-mediated platelet mitochondrial dysfunction through up-regulating the cAMP/PKA signaling pathway in vitro and in vivo. Xinyu Zhou, Xinhui Huang, Chunting Wu, Yongjie Ma, Weiqi Li, Jinqiu Hu, Rong Li, Fuli Ya
, Food Funct.
, 2023
, 14
, 3613
- An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles. Stephen C. L. Hall, Cecilia Tognoloni, Jack Charlton, Éilís C. Bragginton, Alice J. Rothnie, Pooja Sridhar, Mark Wheatley, Timothy J. Knowles, Thomas Arnold, Karen J. Edler, Tim R. Dafforn
, Nanoscale
, 2018
, 10
, 10609
- AI-based identification of therapeutic agents targeting GPCRs: introducing ligand type classifiers and systems biology. Jonas Goßen, Rui Pedro Ribeiro, Dirk Bier, Bernd Neumaier, Paolo Carloni, Alejandro Giorgetti, Giulia Rossetti
, Chem. Sci.
, 2023
, 14
, 8651
- Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models. Claudio N. Cavasotto, Damián Palomba
, Chem. Commun.
, 2015
, 51
, 13576
- Navigating in chromone chemical space: discovery of novel and distinct A3 adenosine receptor ligands. F. Cagide, A. Gaspar, J. Reis, D. Chavarria, S. Vilar, G. Hripcsak, E. Uriarte, S. Kachler, K. N. Klotz, F. Borges
, RSC Adv.
, 2015
, 5
, 78572