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- Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924. Dominik Andre Megger, Shadi Abou-Eid, Birgit Zülch, Barbara Sitek
, Mol. Omics
, 2018
, 14
, 450
- An alternative and efficient synthesis of MLN4924, a selective NEDD8 inhibitor. Hong-Rae Kim, Young Eum Hyun, Dnyandev B. Jarhad, Jinha Yu, Lak Shin Jeong
, Org. Chem. Front.
, 2019
, 6
, 2480
- OligoTRAFTACs: A generalizable method for transcription factor degradation. Kusal T. G. Samarasinghe, Elvira An, Miriam A. Genuth, Ling Chu, Scott A. Holley, Craig M. Crews
, RSC Chem. Biol.
, 2022
, 3
, 1144
- Development of hypoxia-activated PROTAC exerting a more potent effect in tumor hypoxia than in normoxia. Weiyan Cheng, Shasha Li, Xueqian Wen, Siyuan Han, Suhua Wang, Han Wei, Zhizhen Song, Yueqin Wang, Xin Tian, Xiaojian Zhang
, Chem. Commun.
, 2021
, 57
, 12852
- A natural product-like inhibitor of NEDD8-activating enzyme. Chung-Hang Leung, Daniel Shiu-Hin Chan, Hui Yang, Ruben Abagyan, Simon Ming-Yuen Lee, Guo-Yuan Zhu, Wang-Fun Fong, Dik-Lung Ma
, Chem. Commun.
, 2011
, 47
, 2511
- PROTAC degraders as chemical probes for studying target biology and target validation. Václav Němec, Martin P. Schwalm, Susanne Müller, Stefan Knapp
, Chem. Soc. Rev.
, 2022
, 51
, 7971
- Small molecules targeting the NEDD8·NAE protein–protein interaction. Chen-Ming Lin, Zhengyang Jiang, Zhe Gao, Maritess Arancillo, Kevin Burgess
, Chem. Sci.
, 2021
, 12
, 1535
- Glycosidase-targeting small molecules for biological and therapeutic applications. Yujun Kim, Hui Li, Joohee Choi, Jihyeon Boo, Hyemi Jo, Ji Young Hyun, Injae Shin
, Chem. Soc. Rev.
, 2023
, 52
, 7036
- Scaffold hopping enables direct access to more potent PROTACs with in vivo activity. George M. Burslem, Daniel P. Bondeson, Craig M. Crews
, Chem. Commun.
, 2020
, 56
, 6890
- Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders. Christian Steinebach, Yuen Lam Dora Ng, Izidor Sosič, Chih-Shia Lee, Sirui Chen, Stefanie Lindner, Lan Phuong Vu, Aleša Bricelj, Reza Haschemi, Marius Monschke, Elisabeth Steinwarz, Karl G. Wagner, Gerd Bendas, Ji Luo, Michael Gütschow, Jan Krönke
, Chem. Sci.
, 2020
, 11
, 3474