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Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease . Ireen Denya, Sarel F. Malan, Adaze B. Enogieru, Sylvester I. Omoruyi, Okobi E. Ekpo, Erika Kapp, Frank T. Zindo, Jacques Joubert
, Med. Chem. Commun.
, 2018
, 9
, 357
Enantioselective bioreduction of benzo-fused cyclic ketones with engineered Candida glabrata ketoreductase 1 – a promising synthetic route to ladostigil (TV3326) . Jingping Ou-yang, Wenhe Zhang, Fengyu Qin, Weiguo Zuo, Shaoyu Xu, Yan Wang, Bin Qin, Song You, Xian Jia
, Org. Biomol. Chem.
, 2017
, 15
, 7374
Biosynthesis of chiral cyclic and heterocyclic alcohols via CO/C–H/C–O asymmetric reactions . Lei Qin, Lunjie Wu, Yao Nie, Yan Xu
, Catal. Sci. Technol.
, 2021
, 11
, 2637
Design of a structural framework with potential use to develop balanced multifunctional agents against Alzheimer's disease . Neng Jiang, Xiao-Bing Wang, Zhong-Rui Li, Su-Yi Li, Sai-Sai Xie, Ming Huang, Ling-Yi Kong
, RSC Adv.
, 2015
, 5
, 14242
Current and emerging therapeutic targets of alzheimer's disease for the design of multi-target directed ligands . Laura Blaikie, Graeme Kay, Paul Kong Thoo Lin
, Med. Chem. Commun.
, 2019
, 10
, 2052
3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease . Dolores Viña, Maria João Matos, Matilde Yáñez, Lourdes Santana, Eugenio Uriarte
, Med. Chem. Commun.
, 2012
, 3
, 213
Alteration of epigenetic program to recover memory and alleviate neurodegeneration: prospects of multi-target molecules . Ganesh N. Pandian, Rhys D. Taylor, Syed Junetha, Abhijit Saha, Chandran Anandhakumar, Thangavel Vaijayanthi, Hiroshi Sugiyama
, Biomater. Sci.
, 2014
, 2
, 1043
Bioinspired design for the assembly of Glypromate® neuropeptide conjugates with active pharmaceutical ingredients . Sara C. Silva-Reis, A. Catarina V. D. dos Santos, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-Dias
, New J. Chem.
, 2020
, 44
, 21049
Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors . Bijo Mathew, Seung Cheol Baek, Della Grace Thomas Parambi, Jae Pil Lee, Monu Joy, P. R. Annie Rilda, Rugma V. Randev, P. Nithyamol, Vijitha Vijayan, Sini T. Inasu, Githa Elizabeth Mathew, Krishnakumar K. Lohidakshan, Girish Kumar Krishnan, Hoon Kim
, Med. Chem. Commun.
, 2018
, 9
, 1871
Concise synthesis of Azilect via cobalt-catalyzed enantioselective hydrogenation in a bio-based solvent . Soumyadeep Chakrabortty, Felix J. de Zwart, Demi D. Snabilié, Ekambaram Balaraman, Joost N. H. Reek, Bas de Bruin, Johannes G. de Vries
, Catal. Sci. Technol.
, 2023
, 13
, 6668