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- Consensus screening for a challenging target: the quest for P-glycoprotein inhibitors. Paolo Governa, Marco Biagi, Fabrizio Manetti, Stefano Forli
, RSC Med. Chem.
, 2024
, 15
, 720
- Active participation of membrane lipids in inhibition of multidrug transporter P-glycoprotein. Karan Kapoor, Shashank Pant, Emad Tajkhorshid
, Chem. Sci.
, 2021
, 12
, 6293
- Extended-ensemble docking to probe dynamic variation of ligand binding sites during large-scale structural changes of proteins. Karan Kapoor, Sundar Thangapandian, Emad Tajkhorshid
, Chem. Sci.
, 2022
, 13
, 4150
- A convenient protonated strategy for constructing nanodrugs from hydrophobic drug-inhibitor conjugates to reverse tumor multidrug resistance. Penghui Wang, Yuling Wang, Xuelin Xia, Jingchun Wu, Jintang Lin, Wei Huang, Deyue Yan
, Nanoscale
, 2024
- Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators. Elisa Barile, Marianna Borriello, Attilio Di Pietro, Agnès Doreau, Caterina Fattorusso, Ernesto Fattorusso, Virginia Lanzotti
, Org. Biomol. Chem.
, 2008
, 6
, 1756
- Discovery of new tricyclic spiroindole derivatives as potent P-glycoprotein inhibitors for reversing multidrug resistance enabled by a synthetic methodology-based library. Tao Yu, Rong Zeng, Yu Guan, Bin Pan, Hong-Wei Li, Jing Gu, Peng-Fei Zheng, Yan Qian, Qin Ouyang
, RSC Med. Chem.
, 2024
- Adaptive mechanisms of resistance to anti-neoplastic agents. Bibiana I. Ferreira, Maria K. Lie, Agnete S. T. Engelsen, Susana Machado, Wolfgang Link, James B. Lorens
, Med. Chem. Commun.
, 2017
, 8
, 53
- Potential anti-MDR agents based on the podophyllotoxin scaffold: synthesis and antiproliferative activity evaluation against chronic myeloid leukemia cells by activating MAPK signaling pathways. Lei Zhang, Zeguo Zhang, Jing Wang, Yongzheng Chen, Fan Chen, Ya Lin, Xinling Zhu
, RSC Adv.
, 2016
, 6
, 2895
- Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer. S. Mohana, M. Ganesan, B. Agilan, R. Karthikeyan, G. Srithar, R. Beaulah Mary, D. Ananthakrishnan, D. Velmurugan, N. Rajendra Prasad, Suresh V. Ambudkar
, Mol. BioSyst.
, 2016
, 12
, 2458
- Live-cell fluorescence imaging: assessment of thioflavin T uptake in human epidermal carcinoma cells. G. S. M. Sundaram, Kristen Binz, Vedica Sharma, Melany Yeung, Vijay Sharma
, Med. Chem. Commun.
, 2018
, 9
, 946