Results
1 -
10 of
162
(Click
here to explore results)
Lipid-mediated delivery of CD47 siRNA aids JQ1 in ensuring simultaneous downregulation of PD-L1 and CD47 and improves antitumor immunotherapy efficacy . Yong Li, Xianying Meng, Guang Chen, Yue Hou, Xuan Wu, Jialiang Wang, Xiuxiu Cong, Kuirong Mao, Chenxi Wu, Hongmei Chen, Xu Sun, Jingjing Zhou, Ye Wang, Yong-Guang Yang, Tianmeng Sun
, Biomater. Sci.
, 2022
, 10
, 6755
E3 ligase ligand chemistries: from building blocks to protein degraders . Izidor Sosič, Aleša Bricelj, Christian Steinebach
, Chem. Soc. Rev.
, 2022
, 51
, 3487
Evaluation of plant-derived semi-synthetic molecules against BRD3-BD2 protein: a computational strategy to combat breast cancer . Sachin Kumar, Vijay Kumar Bhardwaj, Rahul Singh, Pralay Das, Rituraj Purohit
, Mol. Syst. Des. Eng.
, 2022
, 7
, 381
Controlling cellular distribution of drugs with permeability modifying moieties . Paul L. Richardson, Violeta L. Marin, Stormy L. Koeniger, Aleksandra Baranczak, Julie L. Wilsbacher, Peter J. Kovar, Patricia E. Bacon-Trusk, Min Cheng, Todd A. Hopkins, Sandra T. Haman, Anil Vasudevan
, Med. Chem. Commun.
, 2019
, 10
, 974
Click chemistry in the development of PROTACs . Ce Yang, Ravi Tripathi, Binghe Wang
, RSC Chem. Biol.
, 2024
, 5
, 189
Chemically induced degradation of epigenetic targets . Md Kabir, Xufen Yu, H. Ümit Kaniskan, Jian Jin
, Chem. Soc. Rev.
, 2023
, 52
, 4313
Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy . Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
, Biomater. Sci.
, 2020
, 8
, 2472
Enzyme-responsive micellar JQ1 induces enhanced BET protein inhibition and immunotherapy of malignant tumors . Zhenqi Zhang, Qiang Zhang, Jiguo Xie, Zhiyuan Zhong, Chao Deng
, Biomater. Sci.
, 2021
, 9
, 6915
An iridium(iii )-based irreversible protein–protein interaction inhibitor of BRD4 as a potent anticancer agent . Hai-Jing Zhong, Lihua Lu, Ka-Ho Leung, Catherine C. L. Wong, Chao Peng, Siu-Cheong Yan, Dik-Lung Ma, Zongwei Cai, Hui-Min David Wang, Chung-Hang Leung
, Chem. Sci.
, 2015
, 6
, 5400
Small molecule-mediated protein knockdown as a new approach to drug discovery . Christopher P. Tinworth, Hannah Lithgow, Ian Churcher
, Med. Chem. Commun.
, 2016
, 7
, 2206