Results
1 -
10 of
121
(Click
here to explore results)
High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds . Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter, Karen L. Leach
, Toxicol. Res.
, 2013
, 2
, 235
Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study . Nora Liu, Sascha Hoogendoorn, Bas van de Kar, Allard Kaptein, Tjeerd Barf, Christoph Driessen, Dmitri V. Filippov, Gijsbert A. van der Marel, Mario van der Stelt, Herman S. Overkleeft
, Org. Biomol. Chem.
, 2015
, 13
, 5147
A novel reactive turn-on probe capable of selective profiling and no-wash imaging of Bruton's tyrosine kinase in live cells . Xin Wang, Nan Ma, Rui Wu, Ke Ding, Zhengqiu Li
, Chem. Commun.
, 2019
, 55
, 3473
4-Aminopyrazolopyrimidine scaffold and its deformation in the design of tyrosine and serine/threonine kinase inhibitors in medicinal chemistry . Xiaolu Chen, Yajiao Huang, Wanghan Xu, Yuepiao Cai, Yuanrong Yang
, RSC Med. Chem.
, 2022
, 13
, 1008
Advances in covalent kinase inhibitors . Ayah Abdeldayem, Yasir S. Raouf, Stefan N. Constantinescu, Richard Moriggl, Patrick T. Gunning
, Chem. Soc. Rev.
, 2020
, 49
, 2617
Target engagement approaches for pharmacological evaluation in animal models . James E. Kath, Aleksandra Baranczak
, Chem. Commun.
, 2019
, 55
, 9241
The right tools for the job: the central role for next generation chemical probes and chemistry-based target deconvolution methods in phenotypic drug discovery . Manuela Jörg, Katrina S. Madden
, RSC Med. Chem.
, 2021
, 12
, 646
Small-molecule probes from bench to bedside: advancing molecular analysis of drug–target interactions toward precision medicine . Sijun Pan, Aixiang Ding, Yisi Li, Yaxin Sun, Yueqin Zhan, Zhenkun Ye, Ning Song, Bo Peng, Lin Li, Wei Huang, Huilin Shao
, Chem. Soc. Rev.
, 2023
, 52
, 5706
Pyrazole-containing pharmaceuticals: target, pharmacological activity, and their SAR studies . Guangchen Li, Yifu Cheng, Chi Han, Chun Song, Niu Huang, Yunfei Du
, RSC Med. Chem.
, 2022
, 13
, 1300
Multifunctional theranostic nanoparticles for multi-modal imaging-guided CAR-T immunotherapy and chemo-photothermal combinational therapy of non-Hodgkin's lymphoma . Bowen Shi, Dan Li, Weiwu Yao, Wenfang Wang, Jiang Jiang, Ruiheng Wang, Fuhua Yan, Han Liu, Huan Zhang, Jian Ye
, Biomater. Sci.
, 2022
, 10
, 2577