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- eCF309: a potent, selective and cell-permeable mTOR inhibitor. Craig Fraser, Neil O. Carragher, Asier Unciti-Broceta
, Med. Chem. Commun.
, 2016
, 7
, 471
- Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold. Daniel J. Baillache, Asier Unciti-Broceta
, RSC Med. Chem.
, 2020
, 11
, 1112
- The allosteric mechanism of mTOR activation can inform bitopic inhibitor optimization. Yonglan Liu, Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov
, Chem. Sci.
, 2024
, 15
, 1003
- Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells. Daniel J. Baillache, Teresa Valero, Álvaro Lorente-Macías, David Jonathan Bennett, Richard J. R. Elliott, Neil O. Carragher, Asier Unciti-Broceta
, RSC Med. Chem.
, 2023
, 14
, 2611
- Designing drugs and chemical probes with the dualsteric approach. Jinyin Zha, Jixiao He, Chengwei Wu, Mingyang Zhang, Xinyi Liu, Jian Zhang
, Chem. Soc. Rev.
, 2023
, 52
, 8651
- 4-Aminopyrazolopyrimidine scaffold and its deformation in the design of tyrosine and serine/threonine kinase inhibitors in medicinal chemistry. Xiaolu Chen, Yajiao Huang, Wanghan Xu, Yuepiao Cai, Yuanrong Yang
, RSC Med. Chem.
, 2022
, 13
, 1008
- 3,4-Diaminopyrazolo[3,4-d]pyrimidines: a new three-component microwave-assisted synthesis and anti-leukemic properties. Jia Hui Ng, Felicia Phei Lin Lim, Edward R. T. Tiekink, Anton V. Dolzhenko
, Org. Biomol. Chem.
, 2023
, 21
, 3432
- On the origins of SARS-CoV-2 main protease inhibitors. Yves L. Janin
, RSC Med. Chem.
, 2024
, 15
, 81
- Synthesis, in vitro and in vivo anticancer activity of novel 1-(4-imino-1-substituted-1H-pyrazolo[3,4-d]pyrimidin-5(4H)-yl)urea derivatives. Chandra Bhushan Mishra, Raj Kumar Mongre, Shikha Kumari, Dong Kee Jeong, Manisha Tiwari
, RSC Adv.
, 2016
, 6
, 24491
- Synthesis and biological evaluation of rapamycin-derived, next generation small molecules. Shiva Krishna Reddy Guduru, Prabhat Arya
, Med. Chem. Commun.
, 2018
, 9
, 27