Results
1 -
10 of
89
(Click
here to explore results)
Lnc-TMEM132D-AS1 as a potential therapeutic target for acquired resistance to osimertinib in non-small-cell lung cancer . Nan Wang, Qilin Zhao, Yutang Huang, Chunjie Wen, Yaji Li, Meihua Bao, Lanxiang Wu
, Mol. Omics
, 2023
, 19
, 238
L718Q mutant EGFR escapes covalent inhibition by stabilizing a non-reactive conformation of the lung cancer drug osimertinib . D. Callegari, K. E. Ranaghan, C. J. Woods, R. Minari, M. Tiseo, M. Mor, A. J. Mulholland, A. Lodola
, Chem. Sci.
, 2018
, 9
, 2740
Insight into the impact of EGFR L792Y/F/H mutations on sensitivity to osimertinib: an in silico study . Daoxing Chen, Liting Zhang, Yanan Liu, Jiali Song, Jingwen Guo, Longxin Wang, Qinqin Xia, Xiaohui Zheng, Yuepiao Cai, Chenglv Hong
, New J. Chem.
, 2021
, 45
, 4756
Investigation of the mechanical effects of targeted drugs on cancerous cells based on atomic force microscopy . Jiajing Zhu, Yanling Tian, Zuobin Wang, Ying Wang, Wenxiao Zhang, Kaige Qu, Zhankun Weng, Xianping Liu
, Anal. Methods
, 2021
, 13
, 3136
Identification of natural flavonoids as novel EGFR inhibitors using DFT, molecular docking, and molecular dynamics . Nayim Sepay, Rina Mondal, Muhanna K. Al-Muhanna, Debajyoti Saha
, New J. Chem.
, 2022
, 46
, 9735
Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies . Qiyue Luan, Jeffrey H. Becker, Celine Macaraniag, Malek G. Massad, Jian Zhou, Takeshi Shimamura, Ian Papautsky
, Lab Chip
, 2022
, 22
, 2364
Effects of targeted lung cancer drugs on cardiomyocytes studied by atomic force microscopy . Can Cheng, Shuwei Wang, Jianjun Dong, Shengli Zhang, Dongliang Yu, Zuobin Wang
, Anal. Methods
, 2023
, 15
, 4077
Simultaneous identification and determination of eleven tyrosine kinase inhibitors by supercritical fluid chromatography-mass spectrometry . Shaomin Zhang, Wei Jin, Yongjian Yang
, Anal. Methods
, 2019
, 11
, 2211
The structure-guided discovery of osimertinib: the first U.S. FDA approved mutant selective inhibitor of EGFR T790M . Sam Butterworth, Darren A. E. Cross, M. Raymond V. Finlay, Richard A. Ward, Michael J. Waring
, Med. Chem. Commun.
, 2017
, 8
, 820
Advances in covalent kinase inhibitors . Ayah Abdeldayem, Yasir S. Raouf, Stefan N. Constantinescu, Richard Moriggl, Patrick T. Gunning
, Chem. Soc. Rev.
, 2020
, 49
, 2617