Results
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22
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- Phosphorothioate modification improves exon-skipping of antisense oligonucleotides based on sulfonyl phosphoramidates in mdx mouse myotubes. Yongdong Su, Prithi Raguraman, Rakesh N. Veedu, Vyacheslav V. Filichev
, Org. Biomol. Chem.
, 2022
, 20
, 3790
- Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics. Joseph O'Sullivan, Jose Muñoz-Muñoz, Graeme Turnbull, Neil Sim, Stuart Penny, Sterghios Moschos
, RSC Adv.
, 2022
, 12
, 20432
- Synthesis and biophysical properties of carbamate-locked nucleic acid (LNA) oligonucleotides with potential antisense applications. Cameron Thorpe, Sven Epple, Benjamin Woods, Afaf H. El-Sagheer, Tom Brown
, Org. Biomol. Chem.
, 2019
, 17
, 5341
- Synthesis of 2′-O-monohaloethoxymethyl-modified RNAs and their duplex formation ability. Rintaro Iwata Hara, Masayuki Kageyama, Koichiro Arai, Naoki Uchiyama, Takeshi Wada
, RSC Adv.
, 2017
, 7
, 41297
- Inhibition of survivin by 2′-O-methyl phosphorothioate-modified steric-blocking antisense oligonucleotides. Yalin Li, Suxiang Chen, Kamal Rahimizadeh, Zhen Zhang, Rakesh N. Veedu
, RSC Adv.
, 2024
, 14
, 13336
- In vivo and in vitro studies of antisense oligonucleotides – a review. Anna Kilanowska, Sylwia Studzińska
, RSC Adv.
, 2020
, 10
, 34501
- Nucleic acid degradation as barrier to gene delivery: a guide to understand and overcome nuclease activity. Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan C. De Smedt, Katrien Remaut
, Chem. Soc. Rev.
, 2024
, 53
, 317
- Emerging modes-of-action in drug discovery. Eric Valeur, Frank Narjes, Christian Ottmann, Alleyn T. Plowright
, Med. Chem. Commun.
, 2019
, 10
, 1550
- Sulfur modification in natural RNA and therapeutic oligonucleotides. Ya Ying Zheng, Ying Wu, Thomas J. Begley, Jia Sheng
, RSC Chem. Biol.
, 2021
, 2
, 990
- Small molecules modulating RNA splicing: a review of targets and future perspectives. Léa Bouton, Agathe Ecoutin, Florian Malard, Sébastien Campagne
, RSC Med. Chem.
, 2024
, 15
, 1109