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- Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor. Ryan E. Cobb, Brian Bae, Zhi Li, Matthew A. DeSieno, Satish K. Nair, Huimin Zhao
, Chem. Commun.
, 2015
, 51
, 2526
- Rapid and flexible synthesis of 1-deoxy-d-xylulose-5-phosphate, the substrate for 1-deoxy-d-xylulose-5-phosphate reductoisomerase. Russell J. Cox, Ana de Andrés-Gómez, Christopher R. A. Godfrey
, Org. Biomol. Chem.
, 2003
, 1
, 3173
- Isoprenoid biosynthesis via the MEP pathway. Synthesis of (3R,4S)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-d-xylulose 5-phosphate, the substrate of the 1-deoxy-d-xylulose 5-phosphate reducto-isomerase. Odile Meyer, Catherine Grosdemange-Billiard, Denis Tritsch, Michel Rohmer
, Org. Biomol. Chem.
, 2003
, 1
, 4367
- Efficient biocatalytic processes for highly valuable terminally phosphorylated C5 to C9 d-ketoses. C. Guérard-Hélaine, M. Debacker, P. Clapés, A. Szekrenyi, V. Hélaine, M. Lemaire
, Green Chem.
, 2014
, 16
, 1109
- The MEP pathway and the development of inhibitors as potential anti-infective agents. Ian Hale, Paul M. O'Neill, Neil G. Berry, Audrey Odom, Raman Sharma
, Med. Chem. Commun.
, 2012
, 3
, 418
- Regulation and metabolic engineering of tanshinone biosynthesis. Pengda Ma, Jingying Liu, Anne Osbourn, Juane Dong, Zongsuo Liang
, RSC Adv.
, 2015
, 5
, 18137
- Antimicrobial N-(2-chlorobenzyl)-substituted hydroxamate is an inhibitor of 1-deoxy-d-xylulose 5-phosphate synthase. Daisuke Hayashi, Nobuo Kato, Tomohisa Kuzuyama, Yasuo Sato, Junko Ohkanda
, Chem. Commun.
, 2013
, 49
, 5535
- Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase. Ravindra P. Jumde, Melissa Guardigni, Robin M. Gierse, Alaa Alhayek, Di Zhu, Zhoor Hamid, Sandra Johannsen, Walid A. M. Elgaher, Philipp J. Neusens, Christian Nehls, Jörg Haupenthal, Norbert Reiling, Anna K. H. Hirsch
, Chem. Sci.
, 2021
, 12
, 7775
- Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr)—evidence of a novel binding mode. Géraldine San Jose, Emily R. Jackson, Eugene Uh, Chinchu Johny, Amanda Haymond, Lindsay Lundberg, Chelsea Pinkham, Kylene Kehn-Hall, Helena I. Boshoff, Robin D. Couch, Cynthia S. Dowd
, Med. Chem. Commun.
, 2013
, 4
, 1099
- Structure, synthesis, biosynthesis, and activity of the characteristic compounds from Ginkgo biloba L.. Xin-Guang Liu, Xu Lu, Wen Gao, Ping Li, Hua Yang
, Nat. Prod. Rep.
, 2022
, 39
, 474