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Ion Channel Drug Discovery, CHAPTER 11 The Therapeutic Potential of hERG1 K+ Channels for Treating Cancer and Cardiac Arrhythmias . John Mitcheson, Annarosa Arcangeli
, 2015
, Pages 258-296
Organic Chemistry of Drug Degradation, CHAPTER 3 Oxidative Degradation
, 2012
, Pages 48-109
Emerging Drugs and Targets for Alzheimer's Disease: Volume 2: Neuronal Plasticity, Chapter 23 Serotonin 5-HT4 Receptors as Pharmacological Targets for the Treatment of Alzheimer's Disease . Isabelle Berque-Bestel, Frank Lezoualc'h
, 2010
, Volume 2
, Pages 169-190
Computational and Structural Approaches to Drug Discovery: Ligand-Protein Interactions, Chapter 12 Computational Prediction of Aqueous Solubility, Oral Bioavailability, P450 Activity and hERG Channel Blockade . David E. Clark
, 2008
, Pages 207-222
Metabolism, Pharmacokinetics and Toxicity of Functional Groups: Impact of Chemical Building Blocks on ADMET, Chapter 4 Primary, Secondary and Tertiary Amines and their Isosteres . D. K. Walker, R. M. Jones, A. N. R. Nedderman, P. A. Wright
, 2010
, Pages 168-209
The Handbook of Medicinal Chemistry: Principles and Practice, CHAPTER 15 Discovery Toxicology In Lead Optimisation . Simone Braggio, Mauro Corsi, Aldo Feriani, Stefano Fontana, Luciana Marocchio, Caterina Virginio
, 2015
, Pages 364-412
Metabolism, Pharmacokinetics and Toxicity of Functional Groups: Impact of Chemical Building Blocks on ADMET, Chapter 1 Drugs and their Structural Motifs . Alexander A. Alex, R. Ian Storer
, 2010
, Pages 1-60
Human-based Systems for Translational Research, Chapter 8 Utility of Human Stem Cells for Drug Discovery . Satyan Chintawar, Martin Graf, Zameel Cader
, 2015
, Pages 162-193
Human Stem Cell Toxicology, Chapter 6 Current Developments in the Use of Human Stem Cell Derived Cardiomyocytes to Examine Drug-induced Cardiotoxicity . Varun Ahuja, Sharad Sharma, Raj Kamboj
, 2016
, Pages 124-159
New Horizons in Predictive Toxicology: Current Status and Application, Chapter 8 Cardiac Toxicity Prediction: To Simplify, or to Integrate, that is the Question . Vivek J. Kadambi, Colleen Synan, Katherine Brewer
, 2012
, Pages 147-156