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A comparative study of the molecular structure, lipophilicity, solubility, acidity, absorption and polar surface area of coumarinic anticoagulants and direct thrombin inhibitors . Milan Remko, Ria Broer, Anna Remková
, RSC Adv.
, 2014
, 4
, 8072
Developing an adult stem cell derived microphysiological intestinal system for predicting oral prodrug bioconversion and permeability in humans . Abhinav Sharma, Liang Jin, Xue Wang, Yue-Ting Wang, David M. Stresser
, Lab Chip
, 2024
, 24
, 339
A comparative study on the analytical performance of a charged aerosol detector and an ultraviolet detector for the RP-LC analysis of dabigatran etexilate in capsules . Raquel M. Bernardi, Felipe B. D'Avila, Vítor Todeschini, Pedro E. Fröehlich, Ana M. Bergold
, Anal. Methods
, 2013
, 5
, 4777
Identification of dabigatran etexilate major degradation pathways by liquid chromatography coupled to multi stage high-resolution mass spectrometry . Fatma Amrani, Philippe-Henri Secrétan, Hassane Sadou-Yayé, Caroline Aymes-Chodur, Mélisande Bernard, Audrey Solgadi, Najet Yagoubi, Bernard Do
, RSC Adv.
, 2015
, 5
, 45068
Design, synthesis, biological evaluation and molecular docking of novel dabigatran derivatives as potential thrombin inhibitors . Chun-Lei Li, Ming-Hui Dong, Yu-Jie Ren, Li-Hua Li
, RSC Adv.
, 2015
, 5
, 23737
Discovery of AZD8165 – a clinical candidate from a novel series of neutral thrombin inhibitors . K. Abrahamsson, P. Andersson, J. Bergman, U. Bredberg, J. Brånalt, A.-C. Egnell, U. Eriksson, D. Gustafsson, K.-J. Hoffman, S. Nielsen, I. Nilsson, S. Pehrsson, M. O. Polla, T. Skjaeret, M. Strimfors, C. Wern, M. Ölwegård-Halvarsson, Y. Örtengren
, Med. Chem. Commun.
, 2016
, 7
, 272
Progress on cocrystallization of poorly soluble NME's in the last decade . Parag Roy, Animesh Ghosh
, CrystEngComm
, 2020
, 22
, 6958
Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data . Sohini Chakraborti, Sneha Bheemireddy, Narayanaswamy Srinivasan
, Mol. Omics
, 2020
, 16
, 474
An injectable in situ lipid phase transition system for sustained delivery of dabigatran etexilate with low burst release . Xuanmiao Zhang, Mei Hu, Guangfei Wei, Mengdi Jia, Tao Gong, Ji Liu
, RSC Adv.
, 2017
, 7
, 56594
Transformation of a selective factor Xa inhibitor rivaroxaban into a dual factor Xa/thrombin inhibitor by modification of the morpholin-3-one moiety . Uroš Trstenjak, Janez Ilaš, Danijel Kikelj
, Med. Chem. Commun.
, 2014
, 5
, 197