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- Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats. Suzanne Geenen, James W. T. Yates, J. Gerry Kenna, Frederic Y. Bois, Ian D. Wilson, Hans V. Westerhoff
, Integr. Biol.
, 2013
, 5
, 877
- Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation. Tomáš Pluskal, Takahiro Nakamura, Alejandro Villar-Briones, Mitsuhiro Yanagida
, Mol. BioSyst.
, 2009
, 6
, 182
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites. Romanas Chaleckis, Masahiro Ebe, Tomáš Pluskal, Itsuo Murakami, Hiroshi Kondoh, Mitsuhiro Yanagida
, Mol. BioSyst.
, 2014
, 10
, 2538
- Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective. Toby J. Athersuch, Daniel J. Antoine, Alan R. Boobis, Muireann Coen, Ann K. Daly, Lucia Possamai, Jeremy K. Nicholson, Ian D. Wilson
, Toxicol. Res.
, 2018
, 7
, 347
- Reciprocal redox interactions of lithium cobalt oxide nanoparticles with nicotinamide adenine dinucleotide (NADH) and glutathione (GSH): toward a mechanistic understanding of nanoparticle-biological interactions. Austin H. Henke, Elizabeth D. Laudadio, Jenny K. Hedlund Orbeck, Ali Abbaspour Tamijani, Khoi Nguyen L. Hoang, Sara E. Mason, Catherine J. Murphy, Z. Vivian Feng, Robert J. Hamers
, Environ. Sci.: Nano
, 2021
, 8
, 1749
- Sheathless capillary electrophoresis-mass spectrometry with a high-sensitivity porous sprayer for cationic metabolome analysis. Akiyoshi Hirayama, Masaru Tomita, Tomoyoshi Soga
, Analyst
, 2012
, 137
, 5026
- A Q-marker screening strategy based on ADME studies and systems biology for Chinese herbal medicine, taking Qianghuo Shengshi decoction in treating rheumatoid arthritis as an example. Jiao Wang, Cimin Tao, Guangzheng Xu, Jiawei Ling, Jie Tong, Bey Hing Goh, Yipeng Xu, Linghui Qian, Yong Chen, Xuesong Liu, Yongjiang Wu, Tengfei Xu
, Mol. Omics
, 2023
, 19
, 769
- An introduction to systems toxicology. Nick J. Plant
, Toxicol. Res.
, 2015
, 4
, 9
- Stimulus-responsive self-assembled prodrugs in cancer therapy. Xiao Dong, Rajeev K. Brahma, Chao Fang, Shao Q. Yao
, Chem. Sci.
, 2022
, 13
, 4239
- Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia. Takushi Ooga, Hajime Sato, Atsushi Nagashima, Kazunori Sasaki, Masaru Tomita, Tomoyoshi Soga, Yoshiaki Ohashi
, Mol. BioSyst.
, 2011
, 7
, 1217