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- Inhibition of the family 20 glycoside hydrolase catalytic modules in the Streptococcus pneumoniae exo-β-d-N-acetylglucosaminidase, StrH. Benjamin Pluvinage, Keith A. Stubbs, Mitchell Hattie, David J. Vocadlo, Alisdair B. Boraston
, Org. Biomol. Chem.
, 2013
, 11
, 7907
- Modifying the phenyl group of PUGNAc: reactivity tuning to deliver selective inhibitors for N-acetyl-d-glucosaminidases. Mitchell Hattie, Nevena Cekic, Aleksandra W. Debowski, David J. Vocadlo, Keith A. Stubbs
, Org. Biomol. Chem.
, 2016
, 14
, 3193
- Gaining insight into the inhibition of glycoside hydrolase family 20 exo-β-N-acetylhexosaminidases using a structural approach.. Tomomi Sumida, Keith A. Stubbs, Makoto Ito, Shigeyuki Yokoyama
, Org. Biomol. Chem.
, 2012
, 10
, 2607
- Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc–imidazole hybrid inhibitor. Bhagavathy Shanmugasundaram, Aleksandra W. Debowski, Rebecca J. Dennis, Gideon J. Davies, David J. Vocadlo, Andrea Vasella
, Chem. Commun.
, 2006
, 4372
- Increase of enzyme activity through specific covalent modification with fragments. John F. Darby, Masakazu Atobe, James D. Firth, Paul Bond, Gideon J. Davies, Peter O'Brien, Roderick E. Hubbard
, Chem. Sci.
, 2017
, 8
, 7772
- O-GlcNAcylation confers protection against Staphylococcus aureus infection in Caenorhabditis elegans through ubiquitination. Loganathan Vigneshwari, Boopathi Balasubramaniam, Sivasamy Sethupathy, Shunmugiah Karutha Pandian, Krishnaswamy Balamurugan
, RSC Adv.
, 2018
, 8
, 23089
- A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase. Keith A. Stubbs, Nelson Zhang, David J. Vocadlo
, Org. Biomol. Chem.
, 2006
, 4
, 839
- Glycosidase-targeting small molecules for biological and therapeutic applications. Yujun Kim, Hui Li, Joohee Choi, Jihyeon Boo, Hyemi Jo, Ji Young Hyun, Injae Shin
, Chem. Soc. Rev.
, 2023
, 52
, 7036
- Chemical approaches to study O-GlcNAcylation. Partha S. Banerjee, Gerald W. Hart, Jin Won Cho
, Chem. Soc. Rev.
, 2013
, 42
, 4345
- O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond. Scott A. Yuzwa, David J. Vocadlo
, Chem. Soc. Rev.
, 2014
, 43
, 6839