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- Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatment. De-Si Pan, Qian-Jiao Yang, Xin Fu, Song Shan, Jing-Zhong Zhu, Kun Zhang, Zhi-Bin Li, Zhi-Qiang Ning, Xian-Ping Lu
, Med. Chem. Commun.
, 2014
, 5
, 1789
- A ‘click’ chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras. Jasmine M. Cross, Megan E. Coulson, Joshua P. Smalley, Wiktoria A. Pytel, Ozair Ismail, Justin S. Trory, Shaun M. Cowley, James T. Hodgkinson
, RSC Med. Chem.
, 2022
, 13
, 1634
- Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity. Nina Reßing, Viktoria Marquardt, Christoph G. W. Gertzen, Andrea Schöler, Alexander Schramm, Thomas Kurz, Holger Gohlke, Achim Aigner, Marc Remke, Finn K. Hansen
, Med. Chem. Commun.
, 2019
, 10
, 1109
- Design, synthesis and antiproliferative evaluation of tetrahydro-β-carboline histone deacetylase inhibitors bearing an aliphatic chain linker. Jing Shi, Jiayun Wang, Xingjie Wang, Chao Qu, Changchun Ye, Xiuli Li, Xin Chen, Zhengshui Xu
, RSC Adv.
, 2024
, 14
, 12762
- Design, synthesis and biological evaluation of VEGFR-2/HDAC dual inhibitors as multitargeted antitumor agents based on fruquintinib and vorinostat. Yali Gao, Fei Li, Xin Ni, Siwang Yang, Han Liu, Xingye Wu, Jieqing Liu, Junjie Ma
, RSC Adv.
, 2023
, 13
, 28462
- Multi-target weapons: diaryl-pyrazoline thiazolidinediones simultaneously targeting VEGFR-2 and HDAC cancer hallmarks. Neha Upadhyay, Kalpana Tilekar, Sabreena Safuan, Alan P. Kumar, Markus Schweipert, Franz-Josef Meyer-Almes, Ramaa C S
, RSC Med. Chem.
, 2021
, 12
, 1540
- Origin and bioactivities of thiosulfinated FK228. Xiangyang Liu, Grant C. Currens, Liang Xue, Yi-Qiang Cheng
, Med. Chem. Commun.
, 2019
, 10
, 538
- Identification of mercaptoacetamide-based HDAC6 inhibitors via a lean inhibitor strategy: screening, synthesis, and biological evaluation. Silke Geurs, Dorien Clarisse, Freya Baele, Jorick Franceus, Tom Desmet, Karolien De Bosscher, Matthias D'hooghe
, Chem. Commun.
, 2022
, 58
, 6239
- Development of novel β-carboline-based hydroxamate derivatives as HDAC inhibitors with DNA damage and apoptosis inducing abilities. Ji Liu, Tingting Wang, Xinyang Wang, Lin Luo, Jing Guo, Yanfu Peng, Qibing Xu, Jiefei Miao, Yanan Zhang, Yong Ling
, Med. Chem. Commun.
, 2017
, 8
, 1213
- Quantitative activity–activity relationship (QAAR) driven design to develop hydroxamate derivatives of pentanoic acids as selective HDAC8 inhibitors: synthesis, biological evaluation and binding mode of interaction studies. Sk. Abdul Amin, Prakruti Trivedi, Nilanjan Adhikari, Ganesh Routholla, Dhanya Vijayasarathi, Sanjib Das, Balaram Ghosh, Tarun Jha
, New J. Chem.
, 2021
, 45
, 17149