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- 2,2-Dimethyl-3,4-dihydro-2H-1,4-benzoxazines as isosteres of 2,2-dimethylchromans acting as inhibitors of insulin release and vascular smooth muscle relaxants. Bernard Pirotte, Xavier Florence, Eric Goffin, Philippe Lebrun
, Med. Chem. Commun.
, 2019
, 10
, 431
- Structural modifications of the potassium channel activator cromakalim: the C-3 position. Derek R. Buckle, Catherine S. V. Houge-Frydrych, Ivan L. Pinto, David G. Smith, John M. Tedder
, J. Chem. Soc., Perkin Trans. 1
, 1991
, 63
- Conformational behaviour of cromakalim and related potassium channel activators. W. Anthony Thomas, Ian W. A. Whitcombe
, J. Chem. Soc., Chem. Commun.
, 1990
, 528
- Conformational and steric modifications of the pyran ring of the potassium-channel activator cromakalim. Derek R. Buckle, Drake S. Eggleston, Catherine S. V. Houge-Frydrych, Ivan L. Pinto, Simon A. Readshaw, David G. Smith, Richard A. B. Webster
, J. Chem. Soc., Perkin Trans. 1
, 1991
, 2763
- Conformational analysis of the novel antihypertensive agent cromakalim (BRL34915). Frederick Cassidy, John M. Evans, Duncan M. Smith, Geoffrey Stemp, Colin Edge, David J. Williams
, J. Chem. Soc., Chem. Commun.
, 1989
, 377
- 4-Amido-3,4-dihydro-2H-1-benzothiopyran-3-ols and their sulphoxide and sulphone derivatives—cromakalim analogues. David G. Smith
, J. Chem. Soc., Perkin Trans. 1
, 1990
, 3187
- A diastereoselective cobalt-mediated synthesis of benzopyrans using a novel variation of an intramolecular Nicholas reaction in the key cyclisation step: optimisation and biological evaluation 1. Alastair Mann, Christophe Muller, Elizabeth Tyrrell
, J. Chem. Soc., Perkin Trans. 1
, 1998
, 1427
- Nitrile-containing pharmaceuticals: target, mechanism of action, and their SAR studies. Xi Wang, Yuanxun Wang, Xuemin Li, Zhenyang Yu, Chun Song, Yunfei Du
, RSC Med. Chem.
, 2021
, 12
, 1650
- A convenient 1,3-dipolar cycloaddition–reduction synthetic sequence from 2-allyloxy-5-nitro-salicylaldehyde to aminobenzopyran-annulated heterocycles. Narsidas J. Parmar, Bhavesh R. Pansuriya, Balvantsingh M. Labana, Rajni Kant, Vivek K. Gupta
, RSC Adv.
, 2013
, 3
, 17527
- Prodrugs as empowering tools in drug discovery and development: recent strategic applications of drug delivery solutions to mitigate challenges associated with lead compounds and drug candidates. Murugaiah A. M. Subbaiah, Jarkko Rautio, Nicholas A. Meanwell
, Chem. Soc. Rev.
, 2024
, 53
, 2099