Results
1 -
10 of
19
(Click
here to explore results)
Integrated proteomic and metabolomic profiling of urine of renal anemia patients uncovers the molecular mechanisms of roxadustat . Xiaoe You, Baochun Guo, Zhen Wang, Hualin Ma, Lixia Liu, Ru Zhou, Yaxuan Zheng, Xinzhou Zhang
, Mol. Omics
, 2023
, 19
, 473
Small-molecule inhibitors of HIF-PHD2: a valid strategy to renal anemia treatment in clinical therapy . Yue Wu, Nan Wang, Yonghua Lei, Tianhan Hu, Qidong You, Xiaojin Zhang
, Med. Chem. Commun.
, 2016
, 7
, 1271
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials . Tzu-Lan Yeh, Thomas M. Leissing, Martine I. Abboud, Cyrille C. Thinnes, Onur Atasoylu, James P. Holt-Martyn, Dong Zhang, Anthony Tumber, Kerstin Lippl, Christopher T. Lohans, Ivanhoe K. H. Leung, Helen Morcrette, Ian J. Clifton, Timothy D. W. Claridge, Akane Kawamura, Emily Flashman, Xin Lu, Peter J. Ratcliffe, Rasheduzzaman Chowdhury, Christopher W. Pugh, Christopher J. Schofield
, Chem. Sci.
, 2017
, 8
, 7651
Luteolin can ameliorate renal interstitial fibrosis-induced renal anaemia through the SIRT1/FOXO3 pathway . Fei Li, Ribao Wei, Mengjie Huang, Jianwen Chen, Ping Li, Yue Ma, Xiangmei Chen
, Food Funct.
, 2022
, 13
, 11896
Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α . Thomas P. Corner, Ryan Z. R. Teo, Yue Wu, Eidarus Salah, Yu Nakashima, Giorgia Fiorini, Anthony Tumber, Amelia Brasnett, James P. Holt-Martyn, William D. Figg, Xiaojin Zhang, Lennart Brewitz, Christopher J. Schofield
, Chem. Sci.
, 2023
, 14
, 12098
Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors . James P. Holt-Martyn, Anthony Tumber, Mohammed Z. Rahman, Kerstin Lippl, William Figg, Michael A. McDonough, Rasheduzzaman Chowdhury, Christopher J. Schofield
, Med. Chem. Commun.
, 2019
, 10
, 500
A small-molecule probe for monitoring binding to prolyl hydroxylase domain 2 by fluorescence polarisation . Zhihong Li, Shuai Zhen, Kaijun Su, Anthony Tumber, Quanwei Yu, Ying Dong, Michael McDonough, Christopher J. Schofield, Xiaojin Zhang
, Chem. Commun.
, 2020
, 56
, 14199
Expanding the “minimalist” small molecule tagging approach to different bioactive compounds . Wenjie Lang, Chaonan Yuan, Biwei Zhu, Sijun Pan, Jian Liu, Jie Luo, Shikun Nie, Qing Zhu, Jun-Seok Lee, Jingyan Ge
, Org. Biomol. Chem.
, 2019
, 17
, 3010
A novel family of small molecule HIF-1 alpha stabilizers for the treatment of diabetic wounds; an integrated in silico , in vitro , and in vivo strategy . Esakkimuthukumar M., Akey Krishna Swaroop, Sunil Kumar Patnaik, Rajesh Kumar R., Praveen T. K., Mudavath Ravi Naik, Jubie S.
, RSC Adv.
, 2022
, 12
, 31293
Kinetic and inhibition studies on human Jumonji-C (JmjC) domain-containing protein 5 . Anthony Tumber, Eidarus Salah, Lennart Brewitz, Thomas P. Corner, Christopher J. Schofield
, RSC Chem. Biol.
, 2023
, 4
, 399