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- For a series of methylindole analogs, reactive metabolite formation is a poor predictor of intrinsic cytotoxicity in human hepatocytes. Chenghong Zhang, Shuguang Ma, Erlie Marie Delarosa, Suzanne Tay, Jasleen Sodhi, Vivek Musinipally, Patricia Chang, Rama Pai, Jason S. Halladay, Dinah Misner, Jane R. Kenny, Cornelis E. C. A. Hop, S. Cyrus Khojasteh
, Toxicol. Res.
, 2014
, 3
, 184
- Online monitoring of hepatic rat metabolism by coupling a liver biochip and a mass spectrometer. Franck Merlier, Rachid Jellali, Eric Leclerc
, Analyst
, 2017
, 142
, 3747
- Comparative pharmacokinetics and bioavailability of intranasal and rectal midazolam formulations relative to buccal administration in rabbits. XiaoMei Zhuang, XiaoYing Wang, Juan Wang, JingLai Li, AiPing Zheng, Chuang Lu, ZhenQing Zhang
, RSC Adv.
, 2015
, 5
, 58880
- Human cytochrome P450 enzyme inhibition profile of three flavonoids isolated from Psoralea corylifolia: in silico predictions and experimental validation. Lili Wang, Yue Hai, Nannan Huang, Xue Gao, Wenli Liu, Xin He
, New J. Chem.
, 2018
, 42
, 10922
- Current developments in LC-MS for pharmaceutical analysis. Marco Beccaria, Deirdre Cabooter
, Analyst
, 2020
, 145
, 1129
- A review on advances in the development of electrochemical sensors for the detection of anesthetic drugs. Ajith Mohan Arjun, Prasannakumari H. Krishna, Anish R. Nath, P. Abdul Rasheed
, Anal. Methods
, 2022
, 14
, 4040
- Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides. Andrew V. Stachulski, Xiaoli Meng
, Nat. Prod. Rep.
, 2013
, 30
, 806
- Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry. Andreas R. Baudy, Monicah A. Otieno, Philip Hewitt, Jinping Gan, Adrian Roth, Douglas Keller, Radhakrishna Sura, Terry R. Van Vleet, William R. Proctor
, Lab Chip
, 2020
, 20
, 215
- Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies. Luca Docci, Nicolò Milani, Thomas Ramp, Andrea A. Romeo, Patricio Godoy, Daniela Ortiz Franyuti, Stephan Krähenbühl, Michael Gertz, Aleksandra Galetin, Neil Parrott, Stephen Fowler
, Lab Chip
, 2022
, 22
, 1187
- Computer-aided discovery of phenylpyrazole based amides as potent S6K1 inhibitors. Yan Yin, Yuxing Sun, Lianhua Zhao, Jinpeng Pan, Yangbo Feng
, RSC Med. Chem.
, 2020
, 11
, 583