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Practical synthesis of fingolimod from diethyl acetamidomalonate . Bhaskar Kandagatla, Vetukuri Venkata Naga Kali Vara Prasada Raju, Narayana Sravan Kumar, Ganta Madhusudhan Reddy, Katkam Srinivas, Javed Iqbal, Rakeshwar Bandichhor, Srinivas Oruganti
, RSC Adv.
, 2013
, 3
, 9687
Syntheses and in vitro biological evaluation of S1PR1 ligands and PET studies of four F-18 labeled radiotracers in the brain of nonhuman primates . Zonghua Luo, Junbin Han, Hui Liu, Adam J. Rosenberg, Delphine L. Chen, Robert J. Gropler, Joel S. Perlmutter, Zhude Tu
, Org. Biomol. Chem.
, 2018
, 16
, 9171
Identification of potent tricyclic prodrug S1P1 receptor modulators . David Marcoux, Hai-Yun Xiao, T. G. Murali Dhar, Jenny Xie, Lois D. Lehman-McKeeman, Dauh-Rurng Wu, Marta Dabros, Xiaoxia Yang, Tracy L. Taylor, Xia D. Zhou, Elizabeth M. Heimrich, Rochelle Thomas, Kim W. McIntyre, Hong Shi, Paul C. Levesque, Huadong Sun, Zheng Yang, Anthony M. Marino, Georgia Cornelius, Celia J. D'Arienzo, Anuradha Gupta, Bala Pragalathan, Richard Rampulla, Arvind Mathur, Ding Ren Shen, Mary Ellen Cvijic, Luisa Salter-Cid, Louis J. Lombardo, Percy H. Carter, Alaric J. Dyckman
, Med. Chem. Commun.
, 2017
, 8
, 725
Study of aqueous phase aggregation of FTY720 (fingolimod hydrochloride) and its effect on DMPC liposomes using fluorescent molecular probes . Jitendriya Swain, Monalisa Mohapatra, Santosh R. Borkar, Indrapal Singh Aidhen, Ashok Kumar Mishra
, Phys. Chem. Chem. Phys.
, 2013
, 15
, 17962
Exploring physicochemical space via a bioisostere of the trifluoromethyl and ethyl groups (BITE): attenuating lipophilicity in fluorinated analogues of Gilenya® for multiple sclerosis . Nathalie Erdeljac, Gerald Kehr, Marie Ahlqvist, Laurent Knerr, Ryan Gilmour
, Chem. Commun.
, 2018
, 54
, 12002
Natural product and natural product derived drugs in clinical trials . Mark S. Butler, Avril A. B. Robertson, Matthew A. Cooper
, Nat. Prod. Rep.
, 2014
, 31
, 1612
A molecular level understanding of interaction between FTY720 (Fingolimod hydrochloride) and DMPC multilamellar vesicles . Jitendriya Swain, Santosh R. Borkar, Indrapal Singh Aidhen, Ashok Kumar Mishra
, RSC Adv.
, 2014
, 4
, 17347
Ultrasound-mediated delivery of RGD-conjugated nanobubbles loaded with fingolimod and superparamagnetic iron oxide nanoparticles: targeting hepatocellular carcinoma and enhancing magnetic resonance imaging . Xin-Min Guo, Jia-Lin Chen, Bao-Hui Zeng, Ji-Chuang Lai, Cui-Yan Lin, Mei-Yan Lai
, RSC Adv.
, 2020
, 10
, 39348
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents . Tiago Rodrigues, Florian Sieglitz, Gonçalo J. L. Bernardes
, Chem. Soc. Rev.
, 2016
, 45
, 6130
Enantioselective total synthesis of the highly selective sphingosine-1-receptor VPC01091 by the Heck desymmetrization of a non-activated cyclopentene-fused spiro-pyrrolidinone . Ismat Ullah Khan, Shivashankar Kattela, Abbas Hassan, Carlos Roque Duarte Correia
, Org. Biomol. Chem.
, 2016
, 14
, 9476