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- Natural product and natural product derived drugs in clinical trials. Mark S. Butler, Avril A. B. Robertson, Matthew A. Cooper
, Nat. Prod. Rep.
, 2014
, 31
, 1612
- Proteasome inhibitors bortezomib and carfilzomib used for the treatment of multiple myeloma do not inhibit the serine protease HtrA2/Omi. Vilmos Csizmadia, Paul Hales, Christopher Tsu, Jingya Ma, Jiejin Chen, Pooja Shah, Paul Fleming, Joseph J. Senn, Vivek J. Kadambi, Larry Dick, Francis S. Wolenski
, Toxicol. Res.
, 2016
, 5
, 1619
- Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells. Martin Kampmann
, Chem. Commun.
, 2017
, 53
, 7162
- Targeting eukaryotic proteases for natural products-based drug development. Fatma H. Al-Awadhi, Hendrik Luesch
, Nat. Prod. Rep.
, 2020
, 37
, 827
- Water-removable ynamide coupling reagent for racemization-free syntheses of peptides, amides, and esters. Tao Liu, Xue Zhang, Zejun Peng, Junfeng Zhao
, Green Chem.
, 2021
, 23
, 9916
- From epoxomicin to carfilzomib: chemistry, biology, and medical outcomes. Kyung Bo Kim, Craig M. Crews
, Nat. Prod. Rep.
, 2013
, 30
, 600
- Targeting coenzyme Q10 synthesis overcomes bortezomib resistance in multiple myeloma. Esther A. Zaal, Harm-Jan de Grooth, Inge Oudaert, Pieter Langerhorst, Sophie Levantovsky, Gijs J. J. van Slobbe, Jeroen W. A. Jansen, Eline Menu, Wei Wu, Celia R. Berkers
, Mol. Omics
, 2022
, 18
, 19
- Natural product scaffolds as inspiration for the design and synthesis of 20S human proteasome inhibitors. Grace E. Hubbell, Jetze J. Tepe
, RSC Chem. Biol.
, 2020
, 1
, 305
- Inhibition mechanism and hot-spot prediction of nine potential drugs for SARS-CoV-2 Mpro by large-scale molecular dynamic simulations combined with accurate binding free energy calculations. Song Luo, Kaifang Huang, Xiaoyu Zhao, Yalong Cong, John Z. H. Zhang, Lili Duan
, Nanoscale
, 2021
, 13
, 8313
- Stability and potential degradation of the α′,β′-epoxyketone pharmacophore on ZnO nanocarriers: insights from reactive molecular dynamics and density functional theory calculations. Cheherazade Trouki, Susanna Monti, Giovanni Barcaro
, J. Mater. Chem. B
, 2023
, 11
, 5870