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5Pharmacological Validation of the Two-Dopamine-Receptor Hypothesis, Clinical Pharmacology in Psychiatry Structural requirements of Na+-dependent antidopaminergic agents: Tropapride, Piquindone, Zetidoline, and Metoclopramide Comparison with Na+-independent ligands, Journal of Computer-Aided Molecular Design Piquindone: this atypical neuroleptic produces improvements in the symptoms of schizophrenia, InPharma Pharmacological Options for the Treatment of Touretteu2019s Disorder, Drugs