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53??-Hydroxy-5??-steroid dehydrogenase, Class 1 ?? Oxidoreductases The endogenous progesterone metabolite, 5??-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells, Endocrine Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma, BMC Cancer Neurosteroids and Sexual Behavior and Reproduction, Reproductive Endocrinology Acute, nongenomic actions of the neuroactive gonadal steroid, 3??-hydroxy-4-pregnen-20-one (3??HP), on FSH release in perifused rat anterior pituitary cells, Endocrine