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6ABT-089: An Orally Effective Cholinergic Channel Modulator (ChCM) with Cognitive Enhancement and Neuroprotective Action, Alzheimer Disease Study of the calcium dynamics of the human ??4??2, ??3??4 and ??1??1???? nicotinic acetylcholine receptors, Naunyn-Schmiedeberg's Archives of Pharmacology Central nicotinic receptor agonists ABT-418, ABT-089, and (?)-nicotine reduce distractibility in adult monkeys, Psychopharmacology Efficacy and safety of the novel ??4??2 neuronal nicotinic receptor partial agonist ABT-089 in adults with attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled crossover study, Psychopharmacology A randomized, double-blind, placebo-controlled crossover study of ??4??2* nicotinic acetylcholine receptor agonist AZD1446 (TC-6683) in adults with attention-deficit/hyperactivity disorder, Psychopharmacology Targeting the Nicotinic Cholinergic System to Treat Attention-Deficit/Hyperactivity Disorder: Rationale and Progress to Date, CNS Drugs