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6Yu P., Laird A. D., Du X., Wu J., Won K.-A., Yamaguchi K., Hsu P. P., Qian F., Jaeger C. T., Zhang W., Buhr C. A., Shen P., Abulafia W., Chen J., Young J., Plonowski A., Yakes F. M., Chu F., Lee M., Bentzien F., Lam S. T., Dale S., Matthews D. J., Lamb P., Foster P..
Characterization of the Activity of the PI3K/mTOR Inhibitor XL765 (SAR245409) in Tumor Models with Diverse Genetic Alterations Affecting the PI3K Pathway, Molecular Cancer Therapeutics, 2014 Papadopoulos K. P., Tabernero J., Markman B., Patnaik A., Tolcher A. W., Baselga J., Shi W., Egile C., Ruiz-Soto R., Laird A. D., Miles D., LoRusso P. M..
Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245409 (XL765), a Novel, Orally Administered PI3K/mTOR Inhibitor in Patients with Advanced Solid Tumors, Clinical Cancer Research, 2014 Jänne Pasi A., Cohen Roger B., Laird A. Douglas, Macé Sandrine, Engelman Jeffrey A., Ruiz-Soto Rodrigo, Rockich Kevin, Xu Jianbo, Shapiro Geoffrey I., Martinez Pablo, Felip Enriqueta.
Phase I Safety and Pharmacokinetic Study of the PI3K/mTOR Inhibitor SAR245409 (XL765) in Combination with Erlotinib in Patients with Advanced Solid Tumors, Journal of Thoracic Oncology, 2014 Dai Congxin, Zhang Bo, Liu Xiaohai, Ma Sihai, Yang Yakun, Yao Yong, Feng Ming, Bao Xinjie, Li Guilin, Wang Janxin, Guo Kai, Ma Wenbin, Xing Bing, Lian Wei, Xiao Jianqi, Cai Feng, Zhang Hongbin, Wang Renzhi.
Inhibition of PI3K/AKT/mTOR Pathway Enhances Temozolomide-Induced Cytotoxicity in Pituitary Adenoma Cell Lines in Vitro and Xenografted Pituitary Adenoma in Female Nude Mice, Endocrinology, 2013 Ghadimi M. P., Lopez G., Torres K. E., Belousov R., Young E. D., Liu J., Brewer K. J., Hoffman A., Lusby K., Lazar A. J., Pollock R. E., Lev D..
Targeting the PI3K/mTOR Axis, Alone and in Combination with Autophagy Blockade, for the Treatment of Malignant Peripheral Nerve Sheath Tumors, Molecular Cancer Therapeutics, 2012 Mirzoeva Olga K., Hann Byron, Hom Yun K., Debnath Jayanta, Aftab Dana, Shokat Kevan, Korn W. Michael.
Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K—mTOR pathway in pancreatic adenocarcinoma, Journal of Molecular Medicine, 2011