Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases, Nature Chemical Biology, 2008 Multi-pathway cellular analysis of compound selectivity, Mol. Biosyst., 2010, 6, 1834. Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents, Chem. Sci., 2013, 4, 1837. Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis, Nanoscale, 2013, 5, 7897. Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors., Bioorganic & medicinal chemistry letters Sonoshita et al.
A whole-animal platform to advance a clinical kinase inhibitor into new disease space.
Nature Chemical Biology, doi: 10.1038/nchembio.2556, published online 22 January 2018 ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness, MedChemComm, 2019