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Ciceri et al..
Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
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Nature Chemical Biology, 2014
[DOI: 10.1038/nchembio.1471]
Javadi M; Richmond TD; Huang K; Barber DL.
CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN.
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The Journal of biological chemistry
[PubMed: 23696637]
[DOI: 10.1074/jbc.M113.475087]
Lasho T; Tefferi A; Pardanani A.
Inhibition of JAK-STAT signaling by TG101348: a novel mechanism for inhibition of KITD816V-dependent growth in mast cell leukemia cells.
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Leukemia
[PubMed: 20485374]
[DOI: 10.1038/leu.2010.109]
Santos FP; Verstovsek S.
JAK2 inhibitors for myelofibrosis: why are they effective in patients with and without JAK2V617F mutation?
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Anti-cancer agents in medicinal chemistry
Hazell AS; Afadlal S; Cheresh DA; Azar A.
Treatment of rats with the JAK-2 inhibitor fedratinib does not lead to experimental Wernicke's encephalopathy.
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Neuroscience letters
[DOI: 10.1016/j.neulet.2017.01.041]
Chean J; Chen CJ; Shively JE.
ETS transcription factor ELF5 induces lumen formation in a 3D model of mammary morphogenesis and its expression is inhibited by Jak2 inhibitor TG101348.
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Experimental cell research
[DOI: 10.1016/j.yexcr.2017.08.008]
Speyer G; Mahendra D; Tran HJ; Kiefer J; Schreiber SL; Clemons PA; Dhruv H; Berens M; Kim S.
DIFFERENTIAL PATHWAY DEPENDENCY DISCOVERY ASSOCIATED WITH DRUG RESPONSE ACROSS CANCER CELL LINES.
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Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
[DOI: 10.1142/9789813207813_0046]
Zhou Y; Li C; Li D; Zheng Y; Wang J.
IL-5 blocks apoptosis and tau hyperphosphorylation induced by A?<sub>25-35</sub> peptide in PC12 cells.
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Journal of physiology and biochemistry
[DOI: 10.1007/s13105-017-0550-8]
Quan Y; Xu H; Han Y; Mespl?de T; Wainberg MA.
JAK-STAT Signaling Pathways and Inhibitors Affect Reversion of Envelope-Mutated HIV-1.
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Journal of virology
[DOI: 10.1128/JVI.00075-17]
Betts BC; Veerapathran A; Pidala J; Anasetti C; Yang H; Horna P; Walton K; Cubitt CL; Gunawan S; Lawrence HR; Lawrence NJ; Sebti SM.
Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function.
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Science translational medicine
[DOI: 10.1126/scitranslmed.aai8269]
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