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8Low Jonathan D., Bartberger Michael D., Chen Kui, Cheng Yuan, Fielden Mark R., Gore Vijay, Hickman Dean, Liu Qingyian, Allen Sickmier E., Vargas Hugo M., Werner Jonathan, White Ryan D., Whittington Douglas A., Wood Stephen, Minatti Ana E..
Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D, Med. Chem. Commun., 2017 Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of ??-secretase inhibitors, Nature Communications Lilly stops phase II ??-secretase inhibitor trial, Reactions Weekly A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-?? 1u201342 peptide in human plasma with utility for studies of Alzheimeru2019s disease therapeutics, Alzheimer's Research & Therapy Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human A??-induced synaptic dysfunction in individual freely behaving pre-plaque transgenic rats: rapid reversal by anti-A?? agents, Acta Neuropathologica Communications BACE1 inhibitor drugs in clinical trials for Alzheimeru2019s disease, Alzheimer's Research & Therapy