The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Ayanna U. Jackson, Juan F. Garcia-Reyes, Jason D. Harper, Joshua S. Wiley, Antonio Molina-Díaz, Zheng Ouyang and R. Graham Cooks.
Analysis of drugs of abuse in biofluids by low temperature plasma (LTP) ionization mass spectrometry, Analyst, 2010, 135, 927.
Hajime Miyaguchi and Hiroyuki Inoue.
Determination of amphetamine-type stimulants, cocaine and ketamine in human hair by liquid chromatography/linear ion trap–Orbitrap hybrid mass spectrometry, Analyst, 2011, 136, 3503.
Javier Sastre Toraño and Hendrikus J. M. van Kan.
Simultaneous determination of the tobacco smoke uptake parameters nicotine, cotinine and thiocyanate in urine, saliva and hair, using gas chromatography-mass spectrometry for characterisation of smoki
ng status of recently exposed subjects, Analyst, 2003, 128, 838.
Yi Fan, Yu-Qi Feng, Shi-Lu Da and Xiao-Ping Gao.
In-tube solid-phase microextraction with poly(methacrylic acid-ethylene glycol dimethacrylate) monolithic capillary for direct high-performance liquid chromatographic determination of ketamine in urin
e samples, Analyst, 2004, 129, 1065.