The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors, Naunyn-Schmiedeberg's Archives of Pharmacology